| Title: | Pheromonotropic activity of naturally occurring pyrokinin insect neuropeptides (FXPRLamide) in Helicoverpa zea |
| Author(s): | Abernathy RL; Nachman RJ; Teal PE; Yamashita O; Tumlinson JH; |
| Address: | "Insect Attractants, Behavior and Basic Biology Research Laboratory, USDA-ARS, Gainesville, FL 32604, USA" |
| DOI: | 10.1016/0196-9781(94)00167-7 |
| ISSN/ISBN: | 0196-9781 (Print) 0196-9781 (Linking) |
| Abstract: | "Insect neuropeptides, having the common C-terminal sequence FXPRLamide X = V, T, S, or G), were tested for phyeromonotropic activity in the moth, Helicoverpa zea. Dose-response studies indicated that locustamyotropin-II or locustapyrokinin-II induced production of more pheromone than was stimulated by the pheromone biosynthesis activating neuropeptide of this moth. Other peptides showed various degrees of pheromonotropic activity. The data indicated that substitution of the variable amino acid in the C-terminal pentapeptide sequence resulted in significant differences in pheromonotropic activity. However, the overall structure of the peptide was also found to be of importance" |
| Keywords: | "Amino Acid Sequence Animals Dose-Response Relationship, Drug Female Insect Hormones/*pharmacology Molecular Sequence Data Moths/*physiology Neuropeptides/*pharmacology Peptide Fragments/chemical synthesis/*pharmacology Pheromones/*biosynthesis Structure-A;" |
| Notes: | "MedlineAbernathy, R L Nachman, R J Teal, P E Yamashita, O Tumlinson, J H eng Comparative Study 1995/01/01 Peptides. 1995; 16(2):215-9. doi: 10.1016/0196-9781(94)00167-7" |
