| Title: | A Jasmonate Signaling Network Activates Root Stem Cells and Promotes Regeneration |
| Author(s): | Zhou W; Lozano-Torres JL; Blilou I; Zhang X; Zhai Q; Smant G; Li C; Scheres B; |
| Address: | "Laboratory of Plant Developmental Biology, Wageningen University and Research, 6708 PB Wageningen, the Netherlands; State Key Laboratory of Plant Genomics and National Center for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. Laboratory of Nematology, Wageningen University and Research, 6708 PB Wageningen, the Netherlands. Laboratory of Plant Developmental Biology, Wageningen University and Research, 6708 PB Wageningen, the Netherlands; KAUST, Thuwall 23955, Saudi Arabia. State Key Laboratory of Plant Genomics and National Center for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. State Key Laboratory of Plant Genomics and National Center for Plant Gene Research (Beijing), Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, 100049 Beijing, China. Laboratory of Plant Developmental Biology, Wageningen University and Research, 6708 PB Wageningen, the Netherlands; Rijk Zwaan R&D, 4793 RS Fijnaart, the Netherlands. Electronic address: ben.scheres@wur.nl" |
| DOI: | 10.1016/j.cell.2019.03.006 |
| ISSN/ISBN: | 1097-4172 (Electronic) 0092-8674 (Linking) |
| Abstract: | "Plants are sessile and have to cope with environmentally induced damage through modification of growth and defense pathways. How tissue regeneration is triggered in such responses and whether this involves stem cell activation is an open question. The stress hormone jasmonate (JA) plays well-established roles in wounding and defense responses. JA also affects growth, which is hitherto interpreted as a trade-off between growth and defense. Here, we describe a molecular network triggered by wound-induced JA that promotes stem cell activation and regeneration. JA regulates organizer cell activity in the root stem cell niche through the RBR-SCR network and stress response protein ERF115. Moreover, JA-induced ERF109 transcription stimulates CYCD6;1 expression, functions upstream of ERF115, and promotes regeneration. Soil penetration and response to nematode herbivory induce and require this JA-mediated regeneration response. Therefore, the JA tissue damage response pathway induces stem cell activation and regeneration and activates growth after environmental stress" |
| Keywords: | "Arabidopsis/metabolism Arabidopsis Proteins/metabolism Cyclins/metabolism Cyclopentanes/*metabolism Gene Expression Regulation, Plant/genetics Herbivory Indoleacetic Acids/metabolism Oxylipins/*metabolism Plant Roots/*metabolism Regeneration/physiology Si;" |
| Notes: | "MedlineZhou, Wenkun Lozano-Torres, Jose L Blilou, Ikram Zhang, Xiaoyue Zhai, Qingzhe Smant, Geert Li, Chuanyou Scheres, Ben eng Research Support, Non-U.S. Gov't 2019/04/09 Cell. 2019 May 2; 177(4):942-956.e14. doi: 10.1016/j.cell.2019.03.006. Epub 2019 Apr 4" |
