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Sensors (Basel)


Title:Identification of a Large Pool of Microorganisms with an Array of Porphyrin Based Gas Sensors
Author(s):Zetola NM; Modongo C; Mathlagela K; Sepako E; Matsiri O; Tamuhla T; Mbongwe B; Martinelli E; Sirugo G; Paolesse R; Di Natale C;
Address:"Department of Radiation Oncology, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA. zetolan@gmail.com. School of Medicine, University of Botswana, Private Bag, Gaborone 0022, Botswana. zetolan@gmail.com. Botswana-University of Pennsylvania Partnership, P.O. Box AC 157 ACH, Gaborone 0022, Botswana. zetolan@gmail.com. Botswana-University of Pennsylvania Partnership, P.O. Box AC 157 ACH, Gaborone 0022, Botswana. ntungwana@yahoo.co.uk. School of Medicine, University of Botswana, Private Bag, Gaborone 0022, Botswana. matlhagelak@mopipi.ub.bw. School of Medicine, University of Botswana, Private Bag, Gaborone 0022, Botswana. enoch.sepako@mopipi.ub.bw. Botswana-University of Pennsylvania Partnership, P.O. Box AC 157 ACH, Gaborone 0022, Botswana. ogopotsem@bup.org.bw. Botswana-University of Pennsylvania Partnership, P.O. Box AC 157 ACH, Gaborone 0022, Botswana. tsaone.tamuhla@gmail.com. Department of Environmental Science, University of Botswana, Private Bag, Gaborone 0022, Botswana. mbongwe@mopipi.ub.bw. Department of Electronic Engineering, University of Rome Tor Vergata, Via Politecnico 1, Roma 00133, Italy. martinelli@ing.uniroma2.it. Centro di Ricerca, Ospedale San Pietro Fatebenefratelli, Via Cassia 600, Roma 00189, Italy. gsirugo@gmail.com. Department of Chemical Science and Technology, University of Rome Tor Vergata, Via della Ricerca Scientifica, Roma 00133, Italy. roberto.paolesse@uniroma2.it. Department of Electronic Engineering, University of Rome Tor Vergata, Via Politecnico 1, Roma 00133, Italy. dinatale@uniroma2.it"
Journal Title:Sensors (Basel)
Year:2016
Volume:20160401
Issue:4
Page Number:466 -
DOI: 10.3390/s16040466
ISSN/ISBN:1424-8220 (Electronic) 1424-8220 (Linking)
Abstract:"The association between volatile compounds (VCs) and microorganisms, as demonstrated by several studies, may offer the ground for a rapid identification of pathogens. To this regard, chemical sensors are a key enabling technology for the exploitation of this opportunity. In this study, we investigated the performance of an array of porphyrin-coated quartz microbalance gas sensors in the identification of a panel of 12 bacteria and fungi. The porphyrins were metal complexes and the free base of a functionalized tetraphenylporphyrin. Our results show that the sensor array distinguishes the VC patterns produced by microorganisms in vitro. Besides being individually identified, bacteria are also sorted into Gram-positive and Gram-negative"
Keywords:Bacteria/classification/*isolation & purification Biosensing Techniques/*methods Fungi/classification/isolation & purification Gases/chemistry/*isolation & purification Porphyrins/chemistry Quartz Crystal Microbalance Techniques/methods Volatile Organic C;
Notes:"MedlineZetola, Nicola M Modongo, Chawangwa Mathlagela, Keikantse Sepako, Enoch Matsiri, Ogopotse Tamuhla, Tsaone Mbongwe, Bontle Martinelli, Eugenio Sirugo, Giorgio Paolesse, Roberto Di Natale, Corrado eng R21 AI105611/AI/NIAID NIH HHS/ 11352830/PHS HHS/ Research Support, N.I.H., Extramural Switzerland 2016/04/05 Sensors (Basel). 2016 Apr 1; 16(4):466. doi: 10.3390/s16040466"

 
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