Title: | In vivo monitoring of volatile metabolic trajectories enables rapid diagnosis of influenza A infection |
Author(s): | Yin Z; Huang W; Singh KD; Chen Z; Chen X; Zhou Z; Yang Z; Sinues P; Li X; |
Address: | "Institute of Mass Spectrometry and Atmospheric Environment, Jinan University, Guangzhou 510632, China. tamylee@jnu.edu.cn" |
ISSN/ISBN: | 1364-548X (Electronic) 1359-7345 (Linking) |
Abstract: | We report that influenza A virus infection induces changes in odor traits that could be captured by real-time high-resolution mass spectrometry in a living mouse model. The most striking changes in the volatile metabolites may be associated mostly to glyoxylate/dicarboxylate metabolism |
Keywords: | Animals Herpesviridae Infections/*diagnosis/metabolism/virology Influenza A virus/isolation & purification Mice Volatile Organic Compounds/*analysis/metabolism; |
Notes: | "MedlineYin, Zhihong Huang, Wenbo Singh, Kapil Dev Chen, Zhaoming Chen, Xing Zhou, Zhen Yang, Zifeng Sinues, Pablo Li, Xue eng England 2021/05/14 Chem Commun (Camb). 2021 May 14; 57(39):4791-4794. doi: 10.1039/d1cc01061a. Epub 2021 Apr 15" |