Title: | Male behavior by knockout |
Address: | "WIN Group of Olfactory Dynamics, Heidelberger Akademie der Wissenschaften and Max-Planck-Institut fur medizinische Forschung, Jahnstrasse 29, D-69120 Heidelberg, Germany" |
DOI: | 10.1016/j.neuron.2007.08.016 |
ISSN/ISBN: | 0896-6273 (Print) 0896-6273 (Linking) |
Abstract: | "A recent paper published by Kimchi, Xu, and Dulac in Nature describes the emergence of male-type sexual behavior in female mice following incapacitation of the accessory olfactory system. The authors argue that this implies a default male-type behavioral pattern that is otherwise constantly inhibited in the female brain by chemical signals transduced in the accessory olfactory system. In addition to reviewing these findings, we suggest in this Preview how these findings in the mouse could have relevance for human behavior" |
Keywords: | "Animals Female Humans Male Mice Mice, Knockout/*physiology Olfactory Bulb/*physiology Sex Attractants/*physiology Sex Characteristics Sex Differentiation/physiology Sexual Behavior, Animal/*physiology Smell/physiology TRPC Cation Channels/genetics Testost;" |
Notes: | "MedlineSpors, Hartwig Sobel, Noam eng News 2007/09/06 Neuron. 2007 Sep 6; 55(5):689-93. doi: 10.1016/j.neuron.2007.08.016" |