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BMC Biol

Title:		Deconstructing pheromone-mediated behavior one layer at a time
Author(s):		Sanchez-Andrade G; Logan DW;
Address:		"Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK. dl5@sanger.ac.uk"
Journal Title:		BMC Biol
Year:		2014
Volume:		20140529
Issue:
Page Number:		33 -
DOI:		10.1186/1741-7007-12-33
ISSN/ISBN:		1741-7007 (Electronic) 1741-7007 (Linking)
Abstract:		"The vomeronasal organ, a sensory structure within the nasal cavity of most tetrapods, detects pheromones that influence socio-sexual behavior. It has two neuronal layers, each patterned by distinct receptor sub-families coupled to different G-proteins. Work recently published in this journal found female mice with one layer genetically inactivated are deficient in a surprisingly wide range of reproductive behaviors, providing new insights into how the nose can influence the brain"
Keywords:		"Animals Female GTP-Binding Proteins/*metabolism Male Pheromones/*pharmacology Reproduction/*drug effects Sexual Behavior, Animal/*drug effects;"
Notes:		"MedlineSanchez-Andrade, Gabriela Logan, Darren W eng Comment England 2014/06/03 BMC Biol. 2014 May 29; 12:33. doi: 10.1186/1741-7007-12-33"