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Nano Lett


Title:Detecting simulated patterns of lung cancer biomarkers by random network of single-walled carbon nanotubes coated with nonpolymeric organic materials
Author(s):Peng G; Trock E; Haick H;
Address:"The Department of Chemical Engineering and Russell Barrie Nanotechnology Institute, Technion-Israel Institute of Technology, Haifa 32000, Israel"
Journal Title:Nano Lett
Year:2008
Volume:20081008
Issue:11
Page Number:3631 - 3635
DOI: 10.1021/nl801577u
ISSN/ISBN:1530-6984 (Print) 1530-6984 (Linking)
Abstract:"An array of chemiresistive random network of single-walled carbon nanotubes coated with nonpolymeric organic materials shows a high potential for diagnosis of lung cancer via breath samples. The sensors array shows excellent discrimination between the volatile organic compounds (VOCs) found in the breath of patients with lung cancer, relative to healthy controls, especially if the sensors array is preceded with either water extractor and/or preconcentrator of VOCs. The pattern compositions of the healthy and cancerous states were determined by gas-chromatography linked with mass-spectroscopy (GC-MS) analysis of real exhaled breath"
Keywords:"Biomarkers, Tumor/*analysis/chemistry/*metabolism Computer Simulation Gas Chromatography-Mass Spectrometry Lung Neoplasms/*diagnosis/*metabolism Nanomedicine/instrumentation/*methods Nanotubes, Carbon/*chemistry Organic Chemicals/chemistry Polymers/chemis;"
Notes:"MedlinePeng, Gang Trock, Elena Haick, Hossam eng Research Support, Non-U.S. Gov't 2008/10/09 Nano Lett. 2008 Nov; 8(11):3631-5. doi: 10.1021/nl801577u. Epub 2008 Oct 8"

 
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