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Can J Microbiol

Title:		Cell surface specific immunoglobulin inhibits alpha factor mediated morphogenesis in Saccharomyces cerevisiae
Author(s):		Merkel GJ; Phelps CL; Roeske RW;
Address:
Journal Title:		Can J Microbiol
Year:		1987
Volume:		33
Issue:		4
Page Number:		331 - 335
DOI:		10.1139/m87-056
ISSN/ISBN:		0008-4166 (Print) 0008-4166 (Linking)
Abstract:		"Immunoglobulins raised from Saccharomyces cerevisiae a and alpha mating type cell envelope preparations inhibited alpha factor mediated morphogenesis of the a cell without inhibiting normal cell division. The Ig responsible for this inhibition was absorbed to both a and alpha whole cells and heat-killed cells, indicating that the immunoglobulin binding sites were exposed on the cell surface and not mating type specific. Additionally, alpha factor mediated cell cycle arrest was not affected by the immunoglobulin preparations, implying that the immunoglobulin was not preventing alpha factor from binding to its receptor"
Keywords:		"Antigens, Surface/immunology Cell Membrane/immunology/physiology *Immunoglobulins Kinetics Mating Factor *Morphogenesis Peptides/*physiology Saccharomyces cerevisiae/growth & development/immunology/*physiology;"
Notes:		"MedlineMerkel, G J Phelps, C L Roeske, R W eng 46-813-4681301/PHS HHS/ SO7RR5371/RR/NCRR NIH HHS/ Research Support, U.S. Gov't, P.H.S. Canada 1987/04/01 Can J Microbiol. 1987 Apr; 33(4):331-5. doi: 10.1139/m87-056"