Title: | "Isolation and primary structure of a novel pheromonotropic neuropeptide structurally related to leucopyrokinin from the armyworm larvae, Pseudaletia separata" |
Author(s): | Matsumoto S; Fonagy A; Kurihara M; Uchiumi K; Nagamine T; Chijimatsu M; Mitsui T; |
Address: | "Institute of Physical and Chemical Research (RIKEN), Saitama, Japan" |
Journal Title: | Biochem Biophys Res Commun |
DOI: | 10.1016/0006-291x(92)91765-i |
ISSN/ISBN: | 0006-291X (Print) 0006-291X (Linking) |
Abstract: | "A novel pheromonotropic neuropeptide has been isolated from a head extract of the armyworm larvae, Pseudaletia separata, by a seven step purification procedure using an in vivo assay with decapitated female moths of Bombyx mori. Amino acid sequence analysis and comparison with synthetic peptides established the primary structure of the peptide, termed Pseudaletia pheromonotropin (Pss PT), as H-Lys-Leu-Ser-Tyr-Asp-Asp-Lys-Val-Phe-Glu-Asn-Val-Glu-Phe-Thr-Pro-Arg-Le u-NH2. Pss PT is structurally related to leucopyrokinin, an insect myotropic neuropeptide, and possesses the C-terminal pentapeptide, Phe-Thr-Pro-Arg-Leu-NH2, responsible for the biological activity" |
Keywords: | "Amino Acid Sequence Animals Bombyx/*genetics Chromatography, High Pressure Liquid Freeze Drying Larva Lepidoptera/*genetics Molecular Sequence Data Neuropeptides/*genetics/isolation & purification Oligopeptides/*genetics Pheromones/*genetics Pyrrolidoneca;" |
Notes: | "MedlineMatsumoto, S Fonagy, A Kurihara, M Uchiumi, K Nagamine, T Chijimatsu, M Mitsui, T eng Comparative Study 1992/01/31 Biochem Biophys Res Commun. 1992 Jan 31; 182(2):534-9. doi: 10.1016/0006-291x(92)91765-i" |