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Molecules

Title:		Fungicidal Activity of Volatile Organic Compounds Emitted by Burkholderia gladioli Strain BBB-01
Author(s):		Lin YT; Lee CC; Leu WM; Wu JJ; Huang YC; Meng M;
Address:		"Graduate Institute of Biotechnology, National Chung Hsing University, 250 Kuo-Kuang Rd., Taichung 40227, Taiwan. Ph.D. Program in Microbial Genomics, National Chung Hsing University, 250 Kuo-Kuang Rd., Taichung 40227, Taiwan"
Journal Title:		Molecules
Year:		2021
Volume:		20210131
Issue:		3
Page Number:		-
DOI:		10.3390/molecules26030745
ISSN/ISBN:		1420-3049 (Electronic) 1420-3049 (Linking)
Abstract:		"A Burkholderia gladioli strain, named BBB-01, was isolated from rice shoots based on the confrontation plate assay activity against several plant pathogenic fungi. The genome of this bacterial strain consists of two circular chromosomes and one plasmid with 8,201,484 base pairs in total. Pangenome analysis of 23 B. gladioli strains suggests that B. gladioli BBB-01 has the closest evolutionary relationship to B. gladioli pv. gladioli and B. gladioli pv. agaricicola. B. gladioli BBB-01 emitted dimethyl disulfide and 2,5-dimethylfuran when it was cultivated in lysogeny broth and potato dextrose broth, respectively. Dimethyl disulfide is a well-known pesticide, while the bioactivity of 2,5-dimethylfuran has not been reported. In this study, the inhibition activity of the vapor of these two compounds was examined against phytopathogenic fungi, including Magnaporthe oryzae, Gibberella fujikuroi, Sarocladium oryzae, Phellinus noxius and Colletotrichumfructicola, and human pathogen Candida albicans. In general, 2,5-dimethylfuran is more potent than dimethyl disulfide in suppressing the growth of the tested fungi, suggesting that 2,5-dimethylfuran is a potential fumigant to control plant fungal disease"
Keywords:		"Antifungal Agents/*metabolism/*pharmacology Burkholderia gladioli/*metabolism Plant Diseases/microbiology/prevention & control Volatile Organic Compounds/*metabolism/*pharmacology 2, 5-dimethylfuran Burkholderia gladioli Magnaporthe oryzae dimethyl disulfi;"
Notes:		"MedlineLin, Ying-Tong Lee, Cheng-Cheng Leu, Wei-Ming Wu, Je-Jia Huang, Yu-Cheng Meng, Menghsiao eng 106-2313-B-005-021-MY3/the Ministry of Science and Technology, Taiwan, ROC/ Switzerland 2021/02/13 Molecules. 2021 Jan 31; 26(3):745. doi: 10.3390/molecules26030745"