Bedoukian   RussellIPM   RussellIPM   Piezoelectric Micro-Sprayer


Home
Animal Taxa
Plant Taxa
Semiochemicals
Floral Compounds
Semiochemical Detail
Semiochemicals & Taxa
Synthesis
Control
Invasive spp.
References

Abstract

Guide

Alphascents
Pherobio
InsectScience
E-Econex
Counterpart-Semiochemicals
Print
Email to a Friend
Kindly Donate for The Pherobase

« Previous Abstract"Chemical composition and antimicrobial activity of volatiles from Degenia velebitica, a European stenoendemic plant of the Brassicaceae family"    Next AbstractNovelty of Italian Grape Ale (IGA) beer: Influence of the addition of Gamay macerated grape must or dehydrated Aleatico grape pomace on the aromatic profile »

Genetics


Title:Disruption of a silencer domain by a retrotransposon
Author(s):Mastrangelo MF; Weinstock KG; Shafer BK; Hedge AM; Garfinkel DJ; Strathern JN;
Address:"Laboratory of Eukaryotic Gene Expression, NCI-Frederick Cancer Research and Development Center, Maryland 21702-1201"
Journal Title:Genetics
Year:1992
Volume:131
Issue:3
Page Number:519 - 529
DOI: 10.1093/genetics/131.3.519
ISSN/ISBN:0016-6731 (Print) 0016-6731 (Linking)
Abstract:"A galactose-inducible Ty element carrying the HIS3 gene has been used as an insertional mutagen to generate alpha-factor resistant mutants. This collection of Ty-induced mutations includes insertions into the gene for the alpha-factor receptor (STE2), several nonspecific STE genes, and mutations that lead to the expression of the normally silent HML alpha locus. The hml alpha 'on' mutations fall into two classes, those that disrupt trans-acting regulators involved in silencing HML alpha and a novel class of mutations that activate HML alpha by insertion at that locus. The hml alpha::Ty 'on' mutations illustrate the unusual ability of these retrotransposons to activate genes by overcoming gene silencing mechanisms. The hml alpha::Ty 'on' mutations include examples of multimeric Ty arrays. Single Ty and solo delta insertion derivatives of these Ty multimers restore the ability of the silencing mechanism to repress HML alpha"
Keywords:"Blotting, Southern *DNA Transposable Elements Electrophoresis, Gel, Pulsed-Field *Gene Expression Regulation, Fungal Genes, Fungal Mating Factor Mutagenesis, Insertional Peptides/*genetics Phenotype Receptors, Cell Surface/genetics Receptors, Mating Facto;"
Notes:"MedlineMastrangelo, M F Weinstock, K G Shafer, B K Hedge, A M Garfinkel, D J Strathern, J N eng N01-CO-74101/CO/NCI NIH HHS/ Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. 1992/07/01 Genetics. 1992 Jul; 131(3):519-29. doi: 10.1093/genetics/131.3.519"

 
Back to top
 
Citation: El-Sayed AM 2024. The Pherobase: Database of Pheromones and Semiochemicals. <http://www.pherobase.com>.
© 2003-2024 The Pherobase - Extensive Database of Pheromones and Semiochemicals. Ashraf M. El-Sayed.
Page created on 16-11-2024