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Pharmazie


Title:Contemporary analytical techniques reveal the secret composition of a 19(th) century Jerusalem Balsam
Author(s):Kurkiewicz S; Pietryja MJ; Dzierzega-Lecznar A; Stepien K; Kurkiewicz M; Blonska-Fajfrowska B; Boryczka S;
Address:"Department of Instrumental Analysis, Sosnowiec, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, Poland;, Email: slawek@sum.edu.pl. Institute of Monastery Medicine, Katowice, Poland. Department of Instrumental Analysis, Sosnowiec, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, Poland. School of Computing Science, University of Glasgow, Scotland, UK. Department of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, Poland. Department of Organic Chemistry, Sosnowiec; Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Katowice, Poland"
Journal Title:Pharmazie
Year:2020
Volume:75
Issue:11
Page Number:611 - 617
DOI: 10.1691/ph.2020.0098
ISSN/ISBN:0031-7144 (Print) 0031-7144 (Linking)
Abstract:"In 1719, Antonio Menzani di Cuna from the Saint Savior monastery published an alcoholic extract formula made from plant and herb resins under the name Jerusalem Balsam. The Balsam gained high popularity due to its remedial benefits. At the end of the 19 th century, Jerusalem Balsam produced by the hermit Johannes Treutler was found to be particularly popular. We analysed a sample of a valuable find coming from the last decade of the 19 th century, making it probably the oldest surviving Jerusalem Balsam in the world. The purpose of this work was to investigate the composition of the historical sample and to try to determine the origin of its components. This was achieved by comparing the profile of volatile compounds extracted from the balsam using HS-SPME technique with the profile characteristic for plant resins as classic ingredients of the Johannes Treutler formula. The use of two chromatographic columns of different polarity, as well as the transformation of the polar components of the sample into TMS derivatives, allowed to obtain new information on the historical composition of the Balsam. Also, it can be stated with high probability that plant resins were indeed used in the production of the Balsam as referred to in the original recipe of Johannes Treutler. We also discuss challenges in determining the original composition of the Balsam"
Keywords:"Balsams/chemistry/*history Chemistry, Pharmaceutical History, 19th Century Humans Israel Resins, Plant/chemistry/*history Solid Phase Microextraction;"
Notes:"MedlineKurkiewicz, S Pietryja, M J Dzierzega-Lecznar, A Stepien, K Kurkiewicz, M Blonska-Fajfrowska, B Boryczka, S eng Historical Article Germany 2020/11/27 Pharmazie. 2020 Nov 1; 75(11):611-617. doi: 10.1691/ph.2020.0098"

 
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