| Title: | "Allyl-isothiocyanate treatment induces a complex transcriptional reprogramming including heat stress, oxidative stress and plant defence responses in Arabidopsis thaliana" |
| Author(s): | Kissen R; Overby A; Winge P; Bones AM; |
| Address: | "Department of Biology, Norwegian University of Science and Technology (NTNU), NO-7491, Trondheim, Norway. Present address: Center for Clinical Pharmacy and Clinical Sciences, School of Pharmaceutical Sciences, Kitasato University, Minato-ku, Tokyo, Japan. Department of Biology, Norwegian University of Science and Technology (NTNU), NO-7491, Trondheim, Norway. atle.bones@bio.ntnu.no" |
| DOI: | 10.1186/s12864-016-3039-x |
| ISSN/ISBN: | 1471-2164 (Electronic) 1471-2164 (Linking) |
| Abstract: | "BACKGROUND: Isothiocyanates (ITCs) are degradation products of the plant secondary metabolites glucosinolates (GSLs) and are known to affect human health as well as plant herbivores and pathogens. To investigate the processes engaged in plants upon exposure to isothiocyanate we performed a genome scale transcriptional profiling of Arabidopsis thaliana at different time points in response to an exogenous treatment with allyl-isothiocyanate. RESULTS: The treatment triggered a substantial response with the expression of 431 genes affected (P < 0.05 and log2 >/= 1 or |
| Keywords: | "Arabidopsis/*drug effects/*genetics Computational Biology/methods Gene Expression Profiling Gene Expression Regulation, Plant/*drug effects Gene Ontology Glucosinolates/metabolism Glutathione/metabolism Heat-Shock Response/*genetics Homeostasis Isothiocya;" |
| Notes: | "MedlineKissen, Ralph Overby, Anders Winge, Per Bones, Atle M eng Research Support, Non-U.S. Gov't England 2016/09/19 BMC Genomics. 2016 Sep 17; 17(1):740. doi: 10.1186/s12864-016-3039-x" |
