Title: | Neural circuits regulating sexual behaviors via the olfactory system in mice |
Address: | "Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan; ERATO Touhara Chemosensory Signal Project, JST, The University of Tokyo, Tokyo 113-8657, Japan. Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan; ERATO Touhara Chemosensory Signal Project, JST, The University of Tokyo, Tokyo 113-8657, Japan. Electronic address: ktouhara@mail.ecc.u-tokyo.ac.jp" |
DOI: | 10.1016/j.neures.2018.10.009 |
ISSN/ISBN: | 1872-8111 (Electronic) 0168-0102 (Linking) |
Abstract: | "Reproduction is essential for any animal species. Reproductive behaviors, or sexual behaviors, are largely shaped by external sensory cues exchanged during sexual interaction. In many animals, including rodents, olfactory cues play a critical role in regulating sexual behavior. What exactly these olfactory cues are and how they impact animal behavior have been a central question in the field. Over the past few decades, many studies have dedicated to identifying an active compound that elicits sexual behavior from crude olfactory components. The identified substance has served as a tool to dissect the sensory processing mechanisms in the olfactory systems. In addition, recent advances in genetic engineering, and optics and microscopic techniques have greatly expanded our knowledge of the neural mechanisms underlying the control of sexual behavior in mice. This review summarizes our current knowledge about how sexual behaviors are controlled by olfactory cues" |
Keywords: | Animals Female Male Mice Nerve Net/enzymology/*physiology Neural Pathways/enzymology/*physiology Olfactory Pathways/*physiology Sexual Behavior/*physiology Olfaction Pheromone Sexual behavior Sexual dimorphism Social behavior Vomeronasal; |
Notes: | "MedlineIshii, Kentaro K Touhara, Kazushige eng Review Ireland 2018/11/06 Neurosci Res. 2019 Mar; 140:59-76. doi: 10.1016/j.neures.2018.10.009. Epub 2018 Oct 30" |