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Regul Toxicol Pharmacol

Title:		Indoor air quality (IAQ) evaluation of a Novel Tobacco Vapor (NTV) product
Author(s):		Ichitsubo H; Kotaki M;
Address:		"Tobacco Science Research Center, Japan Tobacco Inc., 6-2 Umegaoka, Aoba-ku, Yokohama, Kanagawa 227-8512, Japan. Electronic address: hirokazu.ichitsubo@jt.com. Corporate, Scientific and Regulatory Affairs Div., Tobacco Business Headquarters, Japan Tobacco Inc., JT Bldg. 2-2-1 Toranomon, Minato-ku, Tokyo, 105-8422, Japan"
Journal Title:		Regul Toxicol Pharmacol
Year:		2018
Volume:		20171223
Issue:
Page Number:		278 - 294
DOI:		10.1016/j.yrtph.2017.12.017
ISSN/ISBN:		1096-0295 (Electronic) 0273-2300 (Linking)
Abstract:		"The impact of using a Novel Tobacco Vapor (NTV) product on indoor air quality (IAQ) was simulated using an environmentally-controlled chamber. Three environmental simulations were examined; two non-smoking areas (conference room and dining room) and one ventilated smoking area (smoking lounge). IAQ was evaluated by (i) measuring constituents in the mainstream NTV product emissions, (ii) and by determining classical environmental tobacco smoke (ETS) and representative air quality markers. Analysis of the mainstream emissions revealed that vapor from the NTV product is chemically simpler than cigarette smoke. ETS markers (RSP, UVPM, FPM, solanesol, nicotine, 3-ethenylpyridine), volatile organic compound (toluene), carbon monoxide, propylene glycol, glycerol, and triacetin were below the limit of detection or the limit of quantification in both the non-smoking and smoking environments after using the NTV product. The concentrations of ammonia, carbonyls (formaldehyde, acetaldehyde, and acetone), and total volatile organic compounds were the same levels found in the chamber without NTV use. There was no significant increase in the levels of formaldehyde, acetone or ammonia in exhaled breath following NTV use. In summary, under the simulations tested, the NTV product had no measurable effect on the IAQ, in either non-smoking or smoking areas"
Keywords:		"Air Pollutants/analysis Air Pollution, Indoor/*analysis Ammonia/chemistry Carbon Monoxide/chemistry Cigarette Smoking/adverse effects Environmental Exposure/analysis Environmental Monitoring/methods Formaldehyde/chemistry Gases/analysis Nicotine/chemistry;"
Notes:		"MedlineIchitsubo, Hirokazu Kotaki, Misato eng Netherlands 2017/12/27 Regul Toxicol Pharmacol. 2018 Feb; 92:278-294. doi: 10.1016/j.yrtph.2017.12.017. Epub 2017 Dec 23"