| Title: | Potential exposure and risk assessment of agricultural workers to the insecticide chlorantraniliprole in rice paddies |
| Author(s): | Lee J; Lee J; Jung M; Shin Y; Kim J; Kim JH; |
| Address: | "Department of Crop Sciences, Konkuk University, Seoul, Republic of Korea. Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea. Department of Applied Biology, College of Natural Resources and Life Science, Dong-A University, Busan, Republic of Korea. Forensic Genetics & Chemistry Division, Supreme Prosecutors' Office, Seoul, Republic of Korea" |
| ISSN/ISBN: | 1526-4998 (Electronic) 1526-498X (Linking) |
| Abstract: | "BACKGROUND: Exposure of agricultural workers in rice paddies to the insecticide chlorantraniliprole and its subsequent potential health risks were investigated during two scenarios (mixing/loading and hand-held spraying). The exposure factors, such as the outer dosimeter, inner dosimeter, gauze, and nitrile gloves, were calculated using whole-body dosimetry to measure dermal exposure. The inhalation exposure was determined using a fiberglass filter which is set with an Institute of Occupational Medicine (IOM) sampler. A recovery test was performed to evaluate the accuracy of the analytical method. RESULTS: The exposure amounts of various matrices were calculated from extraction volume and concentration of the target compound. The dermal exposure to chlorantraniliprole was 0.6 mg [0.001% of the total active ingredient (a.i.)] for mixing and loading, and 28.6 mg (0.066% of the total a.i.) for application. The inhalation exposure to chlorantraniliprole was 7.2 mug (1.3%, 1.2 x 10(-5) % of the total applied a.i.) for mixing and loading, and 1.9 mug (0.006%, 4.4 x 10(-6) % of the total applied a.i.) for application. The most exposed part of the body was the hand (90.4%) during mixing and loading, whereas the primary sites during application were the thighs (32.8%) and shins (22.6%). For mixing and loading, the amount of actual dermal exposure was 5.5 mug day(-1) and that of actual inhalation exposure was 21.9 mug day(-1) . By contrast, in the application, the amounts of actual dermal and actual inhalation exposures were 34 178.7 and 5.9 mug day(-1) , respectively. CONCLUSIONS: The risk assessment results demonstrated that the risk of chlorantraniliprole exposure in rice paddies was low during application than during mixing and loading. (c) 2022 Society of Chemical Industry" |
| Keywords: | Humans *Insecticides/analysis *Oryza *Occupational Exposure/analysis Farmers Risk Assessment Inhalation Exposure/analysis IOM sampler chlorantraniliprole exposure whole-body dosimetry; |
| Notes: | "MedlineLee, Jiho Lee, Junghak Jung, Minwoo Shin, Yongho Kim, JiWoo Kim, Jeong-Han eng Rural Development Administration/ England 2022/10/14 Pest Manag Sci. 2023 Feb; 79(2):678-687. doi: 10.1002/ps.7235. Epub 2022 Oct 27" |
