| Title: | "Human symptom responses to bioeffluents, short-chain carbonyls/acids, and long-chain carbonyls in a simulated aircraft cabin environment" |
| Author(s): | Weisel CP; Fiedler N; Weschler CJ; Ohman-Strickland PA; Mohan KR; McNeil K; Space DR; |
| Address: | "Environmental and Occupational Health Sciences Institute, School of Public Health, Rutgers University, Piscataway, NJ, USA. Environmental and Occupational Health Sciences Institute, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA. Environmental Control Systems, Boeing Commercial Aircraft Group, Seattle, WA, USA" |
| ISSN/ISBN: | 1600-0668 (Electronic) 0905-6947 (Print) 0905-6947 (Linking) |
| Abstract: | "Occupants of aircraft have reported an array of symptoms related to general discomfort and irritation. Volatile organic compounds (VOCs) have been suggested to contribute to the reported symptoms. VOCs are from products used, bioeffluents from people and oxidation reaction products. Thirty-six healthy, young female subjects rated symptoms and environmental quality during an eight-hour exposure to groups of compounds often present in aircraft: (i) long-chain carbonyls, (ii) simulated bioeffluents, and (iii) short-chain carbonyls/organic acids. Statistically more symptoms were identified for the simulated bioeffluents and, to a lesser extent, short-chain carbonyls/organic acids compared to a control condition, although they remained in the acceptable range. There were three temporal patterns in the environmental quality and symptom reports: (i) an adaptive response (immediate increases followed by a decline); (ii) an apparent physiological effect (increases one to three hours into the exposure that remained elevated); and (iii) no statistical differences in reported environmental quality or symptom severity compared to the control air conditions. Typical concentrations found in aircraft can cause transitory symptoms in healthy individuals questioning the adequacy of current standards. Understanding the effects on individuals sensitive to air pollutants and methods to remove the compounds causing the greatest symptom responses are needed" |
| Keywords: | "Adaptation, Physiological Adolescent Adult *Air Pollution, Indoor Aircraft Environmental Exposure/*adverse effects Female Healthy Volunteers Humans Organic Chemicals/*adverse effects Young Adult aircraft cabin bioeffluents controlled study symptom reports;" |
| Notes: | "MedlineWeisel, C P Fiedler, N Weschler, C J Ohman-Strickland, P A Mohan, K R McNeil, K Space, D R eng P30 ES005022/ES/NIEHS NIH HHS/ England 2017/04/26 Indoor Air. 2017 Nov; 27(6):1154-1167. doi: 10.1111/ina.12392. Epub 2017 Jun 26" |
