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Indoor Air

Title:		Health risk assessment of volatile organic compounds at daycare facilities
Author(s):		Bayati M; Vu DC; Vo PH; Rogers E; Park J; Ho TL; Davis AN; Gulseven Z; Carlo G; Palermo F; McElroy JA; Nagel SC; Lin CH;
Address:		"Center for Agroforestry, University of Missouri, Columbia, MO, USA. Department of Environmental Engineering, Tikrit University, Tikrit, Iraq. Department of Civil and Environmental Engineering, University of Missouri, Columbia, MO, USA. Faculty of Technology, Van Lang University, Ho Chi Minh City, Vietnam. School of Natural Resources, University of Missouri, Columbia, MO, USA. Center of Core Facilities, Cuu Long Delta Rice Research Institute, Can Tho, Vietnam. Department of Individual, Family, and Community Education, University of New Mexico, Albuquerque, NM, USA. School of Education, University of California Irvine, Irvine, CA, USA. Department of Human Development and Family Science, Center for Children and Families Across Cultures, University of Missouri, Columbia, MO, USA. Department of Family and Community Medicine, University of Missouri, Columbia, MO, USA. Department of Obstetrics, Gynecology and Women's Health, School of Medicine, University of Missouri, Columbia, MO, USA"
Journal Title:		Indoor Air
Year:		2021
Volume:		20210215
Issue:		4
Page Number:		977 - 988
DOI:		10.1111/ina.12801
ISSN/ISBN:		1600-0668 (Electronic) 0905-6947 (Linking)
Abstract:		"Children are particularly vulnerable to many classes of the volatile organic compounds (VOCs) detected in indoor environments. The negative health impacts associated with chronic and acute exposures of the VOCs might lead to health issues such as genetic damage, cancer, and disorder of nervous systems. In this study, 40 VOCs including aldehydes and ketones, aliphatic hydrocarbons, esters, aromatic hydrocarbons, cyclic terpenes, alcohols, and glycol ethers were identified and qualified in different locations at the University of Missouri (MU) Child Development Laboratory (CDL) in Columbia, Missouri. Our results suggested that the concentrations of the VOCs varied significantly among classrooms, hallways, and playground. The VOCs emitted from personal care and cleaning products had the highest indoor levels (2-ethylhexanol-1, 3-carene, homomenthyl salicylate with mean concentration of 5.15 microg/m(3) , 1.57 microg/m(3) , and 1.47 microg/m(3) , respectively). A cancer risk assessment was conducted, and none of the 95th percentile dose estimates exceeded the age-specific no significant risk levels (NSRL) in all classrooms. Dimensionless toxicity index scores were calculated for all VOCs using a novel web-based framework called Toxicological Prioritization Index (ToxPi), which integrates multiple sources of toxicity data. According to the method, homomenthyl salicylate, benzothiazole, 2-ethylhexyl salicylate, hexadecane, and tridecane exhibited diverse toxicity profiles and ranked as the five most toxic indoor VOCs. The findings of this study provide critical information for policy makers and early education professionals to mitigate the potentially negative health impacts of indoor VOCs in the childcare facilities"
Keywords:		"*Air Pollutants/analysis/toxicity *Air Pollution, Indoor/analysis/statistics & numerical data Child Environmental Monitoring Humans Risk Assessment *Volatile Organic Compounds/analysis/toxicity VOCs child development laboratory childcare health risk asses;"
Notes:		"MedlineBayati, Mohamed Vu, Danh C Vo, Phuc H Rogers, Elizabeth Park, Jihyun Ho, Thi L Davis, Alexandra N Gulseven, Zehra Carlo, Gustavo Palermo, Francisco McElroy, Jane A Nagel, Susan C Lin, Chung-Ho eng Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. England 2021/02/16 Indoor Air. 2021 Jul; 31(4):977-988. doi: 10.1111/ina.12801. Epub 2021 Feb 15"