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Molecules

Title:		Bauhinia forficata Link Infusions: Chemical and Bioactivity of Volatile and Non-Volatile Fractions
Author(s):		Jung EP; de Freitas BP; Kunigami CN; Moreira DL; de Figueiredo NG; Ribeiro LO; Moreira RFA;
Address:		"Laboratory of Organic and Inorganic Chemical Analysis, National Institute of Technology, Rio de Janeiro 20081-312, Brazil. Faculty of Chemical Engineering, Federal University of Fluminense, Niteroi 24210-240, Brazil. Laboratory of Natural Products, Rio de Janeiro Botanical Garden Research Institute, Rio de Janeiro 22460-030, Brazil. Laboratory of Tobacco and Derivatives, National Institute of Technology, Rio de Janeiro 20081-312, Brazil. Food and Nutrition Graduate Program, Federal University of Rio de Janeiro State (UNIRIO), Rio de Janeiro 22290-250, Brazil"
Journal Title:		Molecules
Year:		2022
Volume:		20220824
Issue:		17
Page Number:		-
DOI:		10.3390/molecules27175415
ISSN/ISBN:		1420-3049 (Electronic) 1420-3049 (Linking)
Abstract:		"This study aimed to evaluate Bauhinia forficata infusions prepared using samples available in Rio de Janeiro, Brazil. As such, infusions at 5% (w/v) of different brands and batches commercialized in the city (CS1, CS2, CS3, and CS4) and samples of plant material botanically identified (BS) were evaluated to determine their total phenolic and flavonoid contents (TPC and TFC), antioxidant capacity (ABTS*+, DPPH*, and FRAP assays), phytochemical profile, volatile compounds, and inhibitory effects against the alpha-amylase enzyme. The results showed that infusions prepared using BS samples had lower TPC, TFC and antioxidant potential than the commercial samples (p < 0.05). The batch averages presented high standard deviations mainly for the commercial samples, corroborating sample heterogeneity. Sample volatile fractions were mainly composed of terpenes (40 compounds identified). In the non-volatile fraction, 20 compounds were identified, with emphasis on the CS3 sample, which comprised most of the compounds, mainly flavonoid derivatives. PCA analysis demonstrated more chemical diversity in non-volatile than volatile compounds. The samples also inhibited the alpha-amylase enzyme (IC50 value: 0.235-0.801 mg RE/mL). Despite the differences observed in this work, B. forficata is recognized as a source of bioactive compounds that can increase the intake of antioxidant compounds by the population"
Keywords:		Antioxidants/chemistry *Bauhinia/chemistry Brazil Flavonoids/pharmacology Plant Extracts/chemistry alpha-Amylases SPME technique antioxidant capacity bioactive compounds phytochemical profile alpha-amylase inhibition 'pata-de-vaca';
Notes:		"MedlineJung, Eliane Przytyk de Freitas, Beatriz Pereira Kunigami, Claudete Norie Moreira, Davyson de Lima de Figueiredo, Natalia Guimaraes Ribeiro, Leilson de Oliveira Moreira, Ricardo Felipe Alves eng E.201.211/2022/Fundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio de Janeiro/ 123-145/National Council for Scientific and Technological Development/ 125-2022/Instituto de Pesquisas Jardim Botanico do Rio de Janeiro/ Switzerland 2022/09/10 Molecules. 2022 Aug 24; 27(17):5415. doi: 10.3390/molecules27175415"