« Previous AbstractA new theory of olfaction based on dispersion-induced optical activity    Next AbstractEssential oil based controlled-release non-toxic evaporating tablet provides effective repellency against Musca domestica »

J Sep Sci

Title:		Flow-modulated targeted signal enhancement for volatile organic compounds
Author(s):		Hayward T; Gras R; Luong J;
Address:		"Dow Chemical Canada, Analytical Technology Center, Fort Saskatchewan, AB, Canada"
Journal Title:		J Sep Sci
Year:		2016
Volume:		20160527
Issue:		12
Page Number:		2284 - 2291
DOI:		10.1002/jssc.201600054
ISSN/ISBN:		1615-9314 (Electronic) 1615-9306 (Linking)
Abstract:		"Comprehensive two-dimensional gas chromatography is a technique that is becoming more widespread within the analytical community, especially in the separation of complex mixtures. Modulation in comprehensive two-dimensional gas chromatography can be achieved by manipulating temperature or flow and offers many advantages such as increased separation power, but one underutilized advantage is increased detectability due to the reduction of peak width from the use of a modulator. A flow modulator was used to selectively target analytes for increased detectability with a standard flame ionization detector operated at 100 Hz, without the need for cryogens or advanced modulation software. By the collection of the entire peak volume followed by peak transfer rather than further separation, an increase of 12 times in peak height and detectability was realized for the analytes tested using an internal loop modulator configuration. An external loop flow modulator configuration allowed for more volatile analytes (with k < 5), and demonstrated an analyte detectability enhancement factor of at least 6. The collection loop size can be readily increased with an external loop configuration to accommodate for these naturally broader peaks. This novel flow modulated targeted signal enhancement approach was applied to industrially significant analyses like the analysis of methanol in a hydrocarbon streams. Methanol was detected at 7 ppb with a conventional flame ionization detector and without the need for pre-concentration"
Keywords:		Flow modulation Gas chromatography Signal enhancement Volatile organic compounds;
Notes:		"PubMed-not-MEDLINEHayward, Taylor Gras, Ronda Luong, Jim eng Germany 2016/04/28 J Sep Sci. 2016 Jun; 39(12):2284-91. doi: 10.1002/jssc.201600054. Epub 2016 May 27"