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Proc Natl Acad Sci U S A

Title:		"Characterization and cDNA cloning of the pheromone-binding protein from the tobacco hornworm, Manduca sexta: a tissue-specific developmentally regulated protein"
Author(s):		Gyorgyi TK; Roby-Shemkovitz AJ; Lerner MR;
Address:		"Section of Molecular Neurobiology, Howard Hughes Medical Institute Research Laboratories, Yale University School of Medicine, New Haven, CT 06510"
Journal Title:		Proc Natl Acad Sci U S A
Year:		1988
Volume:		85
Issue:		24
Page Number:		9851 - 9855
DOI:		10.1073/pnas.85.24.9851
ISSN/ISBN:		0027-8424 (Print) 1091-6490 (Electronic) 0027-8424 (Linking)
Abstract:		"cDNA encoding pheromone-binding protein (PBP), the major soluble protein in olfactory sensilla of male moths, has been cloned from the tobacco hornworm, Manduca sexta. A study of the developmental time course of PBP reveals that it is first synthesized just prior to eclosion and that the percentage of antennal mRNA encoding PBP shifts from zero to about 20% at that time. PBP is also found in sensilla from female M. sexta antennae. No amino acid sequence homology is observed between PBP and the vertebrate odorant-binding protein"
Keywords:		"Amino Acid Sequence Animals Base Sequence *Cloning, Molecular DNA/*analysis Female Insect Hormones/*genetics/metabolism *Insect Proteins Lepidoptera Molecular Sequence Data;"
Notes:		"MedlineGyorgyi, T K Roby-Shemkovitz, A J Lerner, M R eng Research Support, Non-U.S. Gov't 1988/12/01 Proc Natl Acad Sci U S A. 1988 Dec; 85(24):9851-5. doi: 10.1073/pnas.85.24.9851"