« Previous AbstractClinical utility of a novel colorimetric chair side test for oral malodour    Next Abstract[Incidence of dominant lethals in the progeny of young male house mice (Mus musculus L.) after exposure to excretory products of mature males of the same species] »

J Clin Periodontol

Title:		Efficacy of different mouthrinse formulations in reducing oral malodour: a randomized clinical trial
Author(s):		Dadamio J; Van Tournout M; Teughels W; Dekeyser C; Coucke W; Quirynen M;
Address:		"Department of Periodontology, Catholic University Leuven, Leuven, Belgium"
Journal Title:		J Clin Periodontol
Year:		2013
Volume:		20130313
Issue:		5
Page Number:		505 - 513
DOI:		10.1111/jcpe.12090
ISSN/ISBN:		1600-051X (Electronic) 0303-6979 (Linking)
Abstract:		"AIMS: The aim of this study was to assess the efficacy of mouthrinses formulations in oral malodour. MATERIAL & METHODS: This single-centre, double-blind, randomized, parallel group clinical trial compared the efficacy of Halita and meridol((R)) with and without zinc lactate versus negative and positive control. Volunteers with confirmed oral malodour (18/group) rinsed with one mouthrinse during 7 days (15 ml, 2x/day for 1 min.). 15 min. after a first rinse (masking effect), and after 7 days (therapeutic effect) the change in organoleptic scores and level of sulphur compounds was recorded. RESULTS: All rinses showed a masking effect (OLS 1 to 2 values reduced), only the rinses with antimicrobial ingredients showed a therapeutic effect (OLS 1 to 1.5 value less). The addition of zinc resulted in a more pronounced masking effect. Halita and meridol((R)) with zinc showed the best therapeutic effect. CONCLUSION: Although the masking effect of the rinses can be attributed partially to a dilution and the effect of aromas, the therapeutic effect should be linked to the anti-microbial action of active ingredients and counter action of zinc ions on VSC. A complete resolution of the unpleasant breath by additional mechanical intervention remains to be proven"
Keywords:		"Amines/chemistry/therapeutic use Anti-Infective Agents/chemistry/therapeutic use Anti-Infective Agents, Local/chemistry/therapeutic use Bacterial Load/drug effects Cetylpyridinium/chemistry/therapeutic use Chemistry, Pharmaceutical Chlorhexidine/analogs &;"
Notes:		"MedlineDadamio, Jesica Van Tournout, Marie Teughels, Wim Dekeyser, Christel Coucke, Wim Quirynen, Marc eng Comparative Study Randomized Controlled Trial Research Support, Non-U.S. Gov't 2013/03/16 J Clin Periodontol. 2013 May; 40(5):505-13. doi: 10.1111/jcpe.12090. Epub 2013 Mar 13"