« Previous AbstractTrans-sexually grafted antennae alter pheromone-directed behaviour in a moth    Next AbstractSemi volatile organic compounds in ambient PM2.5. Seasonal trends and daily resolved source contributions »

Mol Cell Biol

Title:		A position effect on the expression of a tRNA gene mediated by the SIR genes in Saccharomyces cerevisiae
Author(s):		Schnell R; Rine J;
Address:
Journal Title:		Mol Cell Biol
Year:		1986
Volume:		6
Issue:		2
Page Number:		494 - 501
DOI:		10.1128/mcb.6.2.494-501.1986
ISSN/ISBN:		0270-7306 (Print) 1098-5549 (Electronic) 0270-7306 (Linking)
Abstract:		The SIR genes of Saccharomyces cerevisiae are responsible for the position-dependent regulation of the a and alpha mating-type genes. Previous work by others has shown that the products of the SIR genes prevent the accumulation of stable transcripts of the a and alpha genes at HML and HMR. Results of this study establish that this regulation is a region-specific effect rather than a gene-specific effect since expression of a tRNA gene placed at HMR is repressed by the products of the SIR genes
Keywords:		"DNA Restriction Enzymes *Genes, Fungal *Genes, Mating Type, Fungal *Genes, Regulator Genotype Mating Factor Nucleic Acid Hybridization Peptides/genetics Phenotype Plasmids RNA, Transfer/*genetics Saccharomyces cerevisiae/*genetics;"
Notes:		"MedlineSchnell, R Rine, J eng GM31105/GM/NIGMS NIH HHS/ Research Support, U.S. Gov't, P.H.S. 1986/02/01 Mol Cell Biol. 1986 Feb; 6(2):494-501. doi: 10.1128/mcb.6.2.494-501.1986"