Title: | A putative pheromone receptor gene expressed in human olfactory mucosa |
Author(s): | Rodriguez I; Greer CA; Mok MY; Mombaerts P; |
Address: | "The Rockefeller University, New York, New York, USA" |
ISSN/ISBN: | 1061-4036 (Print) 1061-4036 (Linking) |
Abstract: | "Pheromones elicit specific behavioural responses and physiological alterations in recipients of the same species. In mammals, these chemical signals are recognized within the nasal cavity by sensory neurons that express pheromone receptors. In rodents, these receptors are thought to be represented by two large multigene families, comprising the V1r and V2r genes, which encode seven-transmembrane proteins. Although pheromonal effects have been demonstrated in humans, V1R or V2R counterparts of the rodent genes have yet to be characterized" |
Keywords: | "Alleles Amino Acid Sequence Animals Blotting, Southern Chemoreceptor Cells/*chemistry/*metabolism *Chemotactic Factors Cloning, Molecular Codon Frameshift Mutation Glycosylation Humans Mice Models, Genetic Molecular Sequence Data Olfactory Mucosa/*metabol;" |
Notes: | "MedlineRodriguez, I Greer, C A Mok, M Y Mombaerts, P eng Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. 2000/09/06 Nat Genet. 2000 Sep; 26(1):18-9. doi: 10.1038/79124" |