| Title: | Volatile organic compounds and metals/metalloids exposure in children after e-waste control: Implications for priority control pollutants and exposure mitigation measures |
| Author(s): | Kuang HX; Li MY; Zhou Y; Li ZC; Xiang MD; Yu YJ; |
| Address: | "State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China. State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China. Electronic address: yuyunjiang@scies.org" |
| DOI: | 10.1016/j.jhazmat.2023.131598 |
| ISSN/ISBN: | 1873-3336 (Electronic) 0304-3894 (Linking) |
| Abstract: | "The decade-long effort to control e-waste in China has made significant progress from haphazard disposal to organized recycling, but environmental research suggests that exposure to volatile organic compounds (VOCs) and metals/metalloids (MeTs) still poses plausible health risks. To investigate the exposure risk faced by children and identify corresponding priority control chemicals, we evaluated the carcinogenic risk (CR), non-CR, and oxidative DNA damage risks of VOCs and MeTs exposure in 673 children from an e-waste recycling area (ER) by measuring urinary exposure biomarker levels. The ER children were generally exposed to high levels of VOCs and MeTs. We observed distinctive VOCs exposure profiles in ER children. In particular, the 1,2-dichloroethane/ethylbenzene ratio and 1,2-dichloroethane were promising diagnostic indexes for identifying e-waste pollution due to their high accuracy (91.4%) in predicting e-waste exposure. Exposure to acrolein, benzene, 1,3-butadiene, 1,2-dichloroethane, acrylamide, acrylonitrile, arsenic, vanadium, copper, and lead posed considerable CR or/and non-CR and oxidative DNA damage risks to children, while changing personal lifestyles, especially enhancing daily physical exercise, may facilitate mitigating these chemical exposure risks. These findings highlight that the exposure risk of some VOCs and MeTs is still non-negligible in regulated ER, and these hazardous chemicals should be controlled as priorities" |
| Keywords: | Humans Child *Environmental Pollutants Environmental Monitoring *Metalloids *Volatile Organic Compounds/toxicity/analysis *Electronic Waste Risk Assessment *Air Pollutants/analysis Metals/toxicity China Carcinogenic risk Non-carcinogenic risk Oxidative DN; |
| Notes: | "MedlineKuang, Hong-Xuan Li, Meng-Yang Zhou, Yang Li, Zhen-Chi Xiang, Ming-Deng Yu, Yun-Jiang eng Research Support, Non-U.S. Gov't Netherlands 2023/05/16 J Hazard Mater. 2023 Aug 5; 455:131598. doi: 10.1016/j.jhazmat.2023.131598. Epub 2023 May 9" |
