| Title: | Synthesis of odorants in flow and their applications in perfumery |
| Author(s): | Kleoff M; Kiler P; Heretsch P; |
| Address: | "Freie Universitat Berlin, Institut fur Chemie und Biochemie, Fabeckstr. 34-36, 14195 Berlin, Germany. ROR: https://ror.org/046ak2485. ISNI: https://www.isni.org/isni/0000000091164836 PK Perfumes, Menifee, California, United States of America. Leibniz Universitat Hannover, Institut fur Organische Chemie, Schneiderberg 1B, 30167 Hannover, Germany. ROR: https://ror.org/0304hq317. ISNI: https://www.isni.org/isni/0000000121632777" |
| ISSN/ISBN: | 1860-5397 (Print) 1860-5397 (Electronic) 1860-5397 (Linking) |
| Abstract: | "Continuous flow technology is a key technology for sustainable manufacturing with numerous applications for the synthesis of fine chemicals. In recent years, the preparation of odorants utilizing the advantages of flow reactors received growing attention. In this review, we give an overview of selected methods for the synthesis of odorants in flow, including heterogeneously catalyzed reactions, gas reactions, and photochemical C-H functionalization processes. After a brief introduction on types of odorants, the presented odorant syntheses are ordered according to the main odor families 'fruity', 'green', 'marine', 'floral', 'spicy', 'woody', 'ambery', and 'musky' and their use and importance for perfumery is briefly discussed" |
| Keywords: | flow chemistry fragrances odorants scents terpenes; |
| Notes: | "PubMed-not-MEDLINEKleoff, Merlin Kiler, Paul Heretsch, Philipp eng Review Germany 2022/07/22 Beilstein J Org Chem. 2022 Jun 27; 18:754-768. doi: 10.3762/bjoc.18.76. eCollection 2022" |
