| Title: | A strategy for the determination of flavor substances in goat milk by liquid chromatography-high resolution mass spectrometry |
| Author(s): | Jia W; Dong X; Shi L; Dai C; Chu X; |
| Address: | "School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an 710021, China. Electronic address: foodjiawei@aliyun.com. School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an 710021, China. School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an 710021, China. Electronic address: daichunji@sust.edu.cn. School of Food and Biological Engineering, Shaanxi University of Science & Technology, Xi'an 710021, China; Chinese Academy of Inspection and Quarantine, Beijing 100123, China. Electronic address: xiaogangchu@aliyun.com" |
| Journal Title: | J Chromatogr B Analyt Technol Biomed Life Sci |
| DOI: | 10.1016/j.jchromb.2020.122274 |
| ISSN/ISBN: | 1873-376X (Electronic) 1570-0232 (Linking) |
| Abstract: | "A new analytical method for untargeted screening of flavor compounds in goat milk and milk flavor using mass spectrometry was developed and validated. All compounds of low molecular weight were considered as candidate chemicals, instead of focusing only on compounds that already have a known affect on the flavor quality of goat milk. High performance liquid chromatography coupled with high resolution quadrupole orbitrap mass spectrometry based on external standard was used to analyse flavor compounds in complex samples. The untargeted screening strategy is data pre-processing, automated componentization, suspect library spectra searching and the retained analytes confirming based on the reference standard solutions. Forty-two flavor compounds were confirmed and analyzed. The established method was validated by considering the guidelines specified in Commission Decision 2002/657/EC and European SANCO/12571/2013 Guideline 2013. This validated method was successfully applied to samples detection, and some unique flavor compounds were found between goat milk and milk flavor samples, which can provide some useful references for the illicit addition of flavors and fragrances in dairy products" |
| Keywords: | "Animals Chromatography, High Pressure Liquid/*methods Goats Limit of Detection Linear Models Milk/*chemistry Reproducibility of Results Volatile Organic Compounds/*analysis/chemistry Flavor compounds Goat milk Milk flavor UHPLC-Q-Orbitrap;" |
| Notes: | "MedlineJia, Wei Dong, Xuyang Shi, Lin Dai, Chunji Chu, Xiaogang eng Netherlands 2020/07/30 J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Sep 1; 1152:122274. doi: 10.1016/j.jchromb.2020.122274. Epub 2020 Jul 19" |
