| Title: | Single-Laboratory Validation of a Gas Chromatographic Method of Direct Determination of Volatile Compounds in Spirit Drinks: Need for an Improved Interlaboratory Study |
| Author(s): | Charapitsa SV; Sytova SN; Korban AL; Sobolenko LN; |
| Address: | "Belarusian State University, Institute for Nuclear Problems, Bobruyskaya St, 11, Minsk, Belarus" |
| ISSN/ISBN: | 1944-7922 (Electronic) 1060-3271 (Linking) |
| Abstract: | "Background: The quality and safety control of an alcoholic drink is mainly the establishment of its chemical content, particularly the quantity of volatile compounds. Objective: A single-laboratory validation of a gas chromatographic method of direct determination of volatile compounds in spirit drinks was conducted. The discussed method applies ethanol, the major volatile component of an alcoholic beverage, as an internal standard. Possible algorithms of method validation based on interlaboratory study were proposed and described. Methods: Seven standard solutions of the following volatile compounds were prepared gravimetrically in 40% (v/v) water-ethanol solution: acetaldehyde, methyl acetate, ethyl acetate, methanol, 2-propanol, 1-propanol, isobutanol, 1-butanol, and isoamylol. Each sample was measured with the proposed method 30 times in repeatability conditions. Results: Flame ionization detector response was linearly correlated with assigned concentrations at a range of 2 to 5000 mg/L of absolute alcohol (AA) with coefficients of determination (R(2)) more than 0.995 for all analyzed components. Repeatability (RSD(r) |
| Keywords: | "Alcoholic Beverages/*analysis Chromatography, Gas Laboratories Volatile Organic Compounds/*analysis;" |
| Notes: | "MedlineCharapitsa, Siarhei V Sytova, Svetlana N Korban, Anton L Sobolenko, Lidia N eng Validation Study England 2018/11/18 J AOAC Int. 2019 Mar 1; 102(2):669-672. doi: 10.5740/jaoacint.18-0258. Epub 2018 Nov 16" |
