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Front Cell Neurosci

Title:		Selectivity of odorant receptors in insects
Author(s):		Bohbot JD; Dickens JC;
Address:		"Invasive Insect Biocontrol and Behavior Laboratory, Plant Sciences Institute, Henry A. Wallace Beltsville Agricultural Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD, USA"
Journal Title:		Front Cell Neurosci
Year:		2012
Volume:		20120713
Issue:
Page Number:		29 -
DOI:		10.3389/fncel.2012.00029
ISSN/ISBN:		1662-5102 (Electronic) 1662-5102 (Linking)
Abstract:		"Insect olfactory receptors (ORs) detect chemicals, shape neuronal physiology, and regulate behavior. Although ORs have been categorized as 'generalists' and 'specialists' based on their ligand spectrum, both electrophysiological studies and recent pharmacological investigations show that ORs specifically recognize non-pheromonal compounds, and that our understanding of odorant-selectivity mirrors our knowledge of insect chemical ecology. As we are progressively becoming aware that ORs are activated through a variety of mechanisms, the molecular basis of odorant-selectivity and the corollary notion of broad-tuning need to be re-examined from a pharmacological and evolutionary perspective"
Keywords:		generalist olfaction olfactory receptor semiochemical specialist;
Notes:		"PubMed-not-MEDLINEBohbot, Jonathan D Dickens, Joseph C eng Switzerland 2012/07/20 Front Cell Neurosci. 2012 Jul 13; 6:29. doi: 10.3389/fncel.2012.00029. eCollection 2012"