| Title: | A Portable Micro-Gas Chromatography with Integrated Photonic Crystal Slab Sensors on Chip |
| Author(s): | Biswas P; Zhang C; Chen Y; Liu Z; Vaziri S; Zhou W; Sun Y; |
| Address: | "Department of Electrical Engineering, University of Texas at Arlington, Arlington, TX 76019, USA" |
| ISSN/ISBN: | 2079-6374 (Electronic) 2079-6374 (Linking) |
| Abstract: | "The miniaturization of gas chromatography (GC) systems has made it possible to utilize the analytical technique in various on-site applications to rapidly analyze complex gas samples. Various types of miniaturized sensors have been developed for micro-gas chromatography (microGC). However, the integration of an appropriate detector in microGC systems still faces a significant challenge. We present a solution to the problem through integration of microGC with photonic crystal slab (PCS) sensors using transfer printing technology. This integration offers an opportunity to utilize the advantages of optical sensors, such as high sensitivity and rapid response time, and at the same time, compensate for the lack of detection specificity from which label-free optical sensors suffer. We transfer printed a 2D defect free PCS on a borofloat glass, bonded it to a silicon microfluidic gas cell or directly to a microfabricated GC column, and then coated it with a gas responsive polymer. Realtime spectral shift in Fano resonance of the PCS sensor was used to quantitatively detect analytes over a mass range of three orders. The integrated microGC-PCS system was used to demonstrate separation and detection of a complex mixture of 10 chemicals. Fast separation and detection (4 min) and a low detection limit (ng) was demonstrated" |
| Keywords: | "*Chromatography, Gas Equipment Design *Lab-On-A-Chip Devices Microtechnology Photons Polymers Silicon gas sensing micro-gas chromatography optofluidics photonic crystals volatile organic compounds;" |
| Notes: | "MedlineBiswas, Priyanka Zhang, Chen Chen, Yudong Liu, Zhonghe Vaziri, Seyedmohsen Zhou, Weidong Sun, Yuze eng RP170747/Cancer Prevention and Research Institute of Texas/ ECCS-1407947/National Science Foundation/ Switzerland 2021/09/26 Biosensors (Basel). 2021 Sep 9; 11(9):326. doi: 10.3390/bios11090326" |
