Title: | "Sex, stress and integrity: the importance of MAP kinases in yeast" |
Address: | "Department of Biochemistry and Molecular Cell Biology, Ludwig Boltzmann Forschungsstelle, University of Vienna, Austria" |
DOI: | 10.1016/0959-437x(94)90096-5 |
ISSN/ISBN: | 0959-437X (Print) 0959-437X (Linking) |
Abstract: | "To coordinate responses to environmental and cell autonomous signals, Saccharomyces cerevisiae utilizes distinct MAP kinase dependent signal transduction pathways. This offers the opportunity to compare the activation and attenuation mechanisms of MAP kinases in a single organism, and raises the issue of how the specificity of the individual signal pathways is maintained. Although many recent advances in our understanding of these pathways are due to biochemical reconstitution experiments, the most surprising results and insights have come from genetic analyses" |
Keywords: | "Adaptation, Physiological *Adaptor Proteins, Signal Transducing Calcium-Calmodulin-Dependent Protein Kinases/genetics/*metabolism *Carrier Proteins Fungal Proteins/physiology Pheromones/physiology Reproduction Saccharomyces cerevisiae/*enzymology/genetics;" |
Notes: | "MedlineAmmerer, G eng Research Support, Non-U.S. Gov't Review England 1994/02/01 Curr Opin Genet Dev. 1994 Feb; 4(1):90-5. doi: 10.1016/0959-437x(94)90096-5" |