Title: | Mammalian pheromone sensing |
Author(s): | Zufall F; Leinders-Zufall T; |
Address: | "Department of Physiology, University of Saarland School of Medicine, Kirrberger Strasse, 66421 Homburg/Saar, Germany. frank-zufall@uks.eu" |
DOI: | 10.1016/j.conb.2007.07.012 |
ISSN/ISBN: | 0959-4388 (Print) 0959-4388 (Linking) |
Abstract: | The traditional distinction that the mammalian main olfactory system recognizes general odor molecules and the accessory (vomeronasal) system detects pheromones is no longer valid. The emerging picture is that both systems have considerable overlap in terms of the chemosignals they detect and the effects that they mediate. Recent investigations have discovered large families of pheromonal signals together with a rich variety of specific receptor systems and nasal detection pathways. Selective genetic targeting of these subsystems should help to unravel their biological role in pheromone-mediated behavioral responses |
Keywords: | Animals Chemoreceptor Cells/physiology Mammals/*physiology Odorants Olfactory Pathways/anatomy & histology/*physiology Pheromones/chemistry/*physiology Smell/*physiology; |
Notes: | "MedlineZufall, Frank Leinders-Zufall, Trese eng Research Support, Non-U.S. Gov't Review England 2007/08/22 Curr Opin Neurobiol. 2007 Aug; 17(4):483-9. doi: 10.1016/j.conb.2007.07.012. Epub 2007 Aug 20" |