| Title: | In situ analysis of solvents on breath and blood: a selected ion flow tube mass spectrometric study |
| Author(s): | Wilson PF; Freeman CG; McEwan MJ; Milligan DB; Allardyce RA; Shaw GM; |
| Address: | "Department of Chemistry, University of Canterbury, Christchurch, New Zealand" |
| Journal Title: | Rapid Commun Mass Spectrom |
| ISSN/ISBN: | 0951-4198 (Print) 0951-4198 (Linking) |
| Abstract: | "We report measurements of residual vapour levels of xylenes and trimethylbenzenes, present following a floor re-surfacing procedure, using the technique of selected ion flow tube mass spectrometry (SIFT-MS). A subject exposed to controlled amounts of xylene and mesitylene was monitored by direct breath exhalation over a 4-hour period after exposure to the volatile organic compounds (VOCs) had stopped. The headspace gases above 5 mL blood samples taken over this period were also monitored. The decays of the solvent levels with time were fitted to a two-compartment model with residence times for xylene and mesitylene of 0.37 h and 0.38 h, respectively (compartment one) and 2.5 h and 2.8 h, respectively (compartment two)" |
| Keywords: | Adult Algorithms Benzene Derivatives/analysis *Breath Tests Humans Male Mass Spectrometry Polyurethanes/analysis Solvents/*analysis Xylenes/analysis; |
| Notes: | "MedlineWilson, Paul F Freeman, Colin G McEwan, Murray J Milligan, Daniel B Allardyce, Randall A Shaw, Geoffrey M eng Clinical Trial Research Support, Non-U.S. Gov't England 2002/02/22 Rapid Commun Mass Spectrom. 2002; 16(5):427-32. doi: 10.1002/rcm.594" |
