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J Gen Microbiol

Title:		Monoclonal antibodies to cell surface antigens involved in sex pheromone induced mating in Streptococcus faecalis
Author(s):		Tortorello M; Adsit J; Krug D; Antczak D; Dunny G;
Address:
Journal Title:		J Gen Microbiol
Year:		1986
Volume:		132
Issue:		4
Page Number:		857 - 864
DOI:		10.1099/00221287-132-4-857
ISSN/ISBN:		0022-1287 (Print) 0022-1287 (Linking)
Abstract:		"Hybridoma cell lines producing monoclonal antibodies to Streptococcus faecalis cell surface antigens were constructed. Some of the antibodies isolated were directed against surface components involved in pheromone-induced mating. This paper describes the use of the monoclonal antibodies to identify antigenically related surface components detected by immunoprecipitation and Western blotting, their use in pheromone response assays, and their use as functional inhibitors in mating experiments"
Keywords:		"Antibodies, Monoclonal Antigens, Surface/*immunology Cell Line Conjugation, Genetic Dose-Response Relationship, Immunologic Enterococcus faecalis/genetics/*immunology Hybridomas Pheromones/*immunology Reproduction Sex Attractants/*immunology;"
Notes:		"MedlineTortorello, M Adsit, J Krug, D Antczak, D Dunny, G eng IR01-AI-19310/AI/NIAID NIH HHS/ Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. England 1986/04/01 J Gen Microbiol. 1986 Apr; 132(4):857-64. doi: 10.1099/00221287-132-4-857"