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J Steroid Biochem Mol Biol

Title:		Migration of LHRH-immunoreactive neurons from the olfactory placode rationalizes olfacto-hormonal relationships
Author(s):		Schwanzel-Fukuda M; Pfaff DW;
Address:		"Laboratory of Neurobiology and Behavior, Rockefeller University, New York, NY 10021"
Journal Title:		J Steroid Biochem Mol Biol
Year:		1991
Volume:		39
Issue:		4B
Page Number:		565 - 572
DOI:		10.1016/0960-0760(91)90254-3
ISSN/ISBN:		0960-0760 (Print) 0960-0760 (Linking)
Abstract:		"Nerve cells that express luteinizing hormone-releasing hormone (LHRH), essential for reproductive functions, originate in the epithelium of the medial olfactory placode. While the peripheral origin of this physiologically important brain peptide is surprising, associations between olfactory and reproductive systems are well documented in behavioral studies of pheromones and in clinical studies of disorders including hypogonadotropic hypogonadism with anosmia or olfactory-genital dysplasia. Mechanisms underlying this migration include a close association with neural cell adhesion molecules (NCAM), but are likely also to involve other physical and chemical factors"
Keywords:		Animals Cell Movement Cranial Nerves/chemistry Gonadotropin-Releasing Hormone/*analysis Humans Immunohistochemistry Neurons/*chemistry/physiology Olfactory Pathways/*chemistry/cytology/embryology Reproduction/physiology Smell/physiology;
Notes:		"MedlineSchwanzel-Fukuda, M Pfaff, D W eng Review England 1991/10/01 J Steroid Biochem Mol Biol. 1991 Oct; 39(4B):565-72. doi: 10.1016/0960-0760(91)90254-3"