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Phytochemistry

Title:		Natural product studies of U.S. endangered plants: volatile components of Lindera melissifolia (Lauraceae) repel mosquitoes and ticks
Author(s):		Oh J; Bowling JJ; Carroll JF; Demirci B; Baser KH; Leininger TD; Bernier UR; Hamann MT;
Address:		"Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS 38677, USA"
Journal Title:		Phytochemistry
Year:		2012
Volume:		20120614
Issue:
Page Number:		28 - 36
DOI:		10.1016/j.phytochem.2012.05.001
ISSN/ISBN:		1873-3700 (Electronic) 0031-9422 (Print) 0031-9422 (Linking)
Abstract:		"The number of endangered plant species in the U.S. is significant, yet studies aimed towards utilizing these plants are limited. Ticks and mosquitoes are vectors of significant pathogenic diseases of humans. Repellents are critical means of personal protection against biting arthropods and disease transmission. The essential oil and solvent extracts from Lindera melissifolia (Walt.) Blume (Lauraceae) (pondberry) drupes were gathered and analyzed by GC and GC-MS. The essential oil obtained from this endangered plant showed a significant dose dependent repellency of ticks and a moderate mosquito repellent effect while the subsequent hexanes extract was completely ineffective. Fractional freezing enriched the tick repellent components of the essential oil. Several known tick repellent components were recognized by the GC-MS comparison of the resulting fractions and beta-caryophyllene, alpha-humulene, germacrene D and beta-elemene warrant evaluations for tick repellency. Identifying pondberry as a potential renewable source for a broad spectrum repellent supports efforts to conserve similar U.S. endangered or threatened plant species"
Keywords:		"Animals Biological Products/analysis/isolation & purification/*pharmacology Culicidae/*drug effects *Endangered Species Female Hexanes/chemistry Humans Insect Repellents/analysis/isolation & purification/*pharmacology Lindera/*chemistry Male Oils, Volatil;"
Notes:		"MedlineOh, Joonseok Bowling, John J Carroll, John F Demirci, Betul Baser, K Husnu Can Leininger, Theodor D Bernier, Ulrich R Hamann, Mark T eng C06 RR014503/RR/NCRR NIH HHS/ R01 AT007318/AT/NCCIH NIH HHS/ C06 RR-14503-01/RR/NCRR NIH HHS/ Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't England 2012/06/19 Phytochemistry. 2012 Aug; 80:28-36. doi: 10.1016/j.phytochem.2012.05.001. Epub 2012 Jun 14"