| Title: | Identification of puberty-accelerating pheromones in male mouse urine |
| Author(s): | Nishimura K; Utsumi K; Yuhara M; Fujitani Y; Iritani A; |
| Address: | "Department of Animal Science, College of Agriculture, Kyoto University, Japan" |
| ISSN/ISBN: | 0022-104X (Print) 0022-104X (Linking) |
| Abstract: | "Gas chromatography-mass spectrometry was employed to identify the two volatile amines in male mouse urine. These amines were much less concentrated in urine of castrated males. The identified amines, isobutylamine and isoamylamine, were assayed for the potential of puberty acceleration in postweaning female mice. A total of 105 young female mice were exposed to one of the following five odors: distilled water (control), 0.1 M isobutylamine, 0.1 M isoamylamine, a mixture of 0.05 M isobutylamine and 0.05 M isoamylamine, or fresh male mouse urine. The mixture of these amines accelerated the vaginal opening of young females. Except for the control, all experimental odors accelerated the first vaginal estrus in ICR strain mice" |
| Keywords: | Amines/*physiology/urine Animals Butylamines/*physiology/urine Female Gas Chromatography-Mass Spectrometry Male Mice Orchiectomy Pheromones/*urine *Sexual Maturation; |
| Notes: | "MedlineNishimura, K Utsumi, K Yuhara, M Fujitani, Y Iritani, A eng Research Support, Non-U.S. Gov't 1989/09/01 J Exp Zool. 1989 Sep; 251(3):300-5. doi: 10.1002/jez.1402510306" |
