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Anim Behav

Title:		"Excreted urine, bladder urine, and the delay of sexual maturation in female house mice"
Author(s):		McIntosh TK; Drickamer LC;
Address:
Journal Title:		Anim Behav
Year:		1977
Volume:		25
Issue:		4
Page Number:		999 - 1004
DOI:		10.1016/0003-3472(77)90051-3
ISSN/ISBN:		0003-3472 (Print) 0003-3472 (Linking)
Abstract:		"A series of experiments tested effects of excreted and bladder urine of group- and singly-caged female house mice (Mus musculus) on sexual maturation of young female mice caged alone or in groups of eight. Puberty was determined by vaginal smears. A maturation-delaying pheromone was present in bladder urine of all female mice and excreted urine of group-caged females, but not in excreted urine from singly-caged females. Test mice treated with bladder urine homogenized with urethras from singly-caged females matured at the same age as controls. Apparently the urethras or associated glands of singly-caged females produce a substance which deactivates the maturation-delaying pheromone contained in bladder urine"
Keywords:		"Animals Female Housing, Animal Male Mice/*urine Pheromones/metabolism/*urine *Sexual Maturation Social Environment Social Isolation Urethra/metabolism;"
Notes:		"MedlineMcIntosh, T K Drickamer, L C eng Research Support, U.S. Gov't, Non-P.H.S. England 1977/11/01 Anim Behav. 1977 Nov; 25(4):999-1004. doi: 10.1016/0003-3472(77)90051-3"