| Title: | The Lutzomyia longipalpis species complex: does population sub-structure matter to Leishmania transmission? |
| Author(s): | Maingon RD; Ward RD; Hamilton JG; Bauzer LG; Peixoto AA; |
| Address: | "Centre for Applied Entomology and Parasitology, Institute of Science & Technology in Medicine, Keele University, Huxley Building, Staffordshire, ST5 5BG, UK" |
| ISSN/ISBN: | 1471-4922 (Print) 1471-4922 (Linking) |
| Abstract: | "Leishmania chagasi causes visceral leishmaniasis and, to a lesser extent, atypical cutaneous leishmaniasis in Central and South America. Its main sand fly vector, Lutzomyia longipalpis s.l. (Diptera: Psychodidae) displays a complex population structure that might contribute to the observed clinical pleomorphism and to recent major urban epidemics. This article summarises our understanding on reproductive barriers and hybridisation among this vector's sibling incipient species. Identifying genes important for sand fly ecological adaptability and sand fly-Leishmania genetic co-variation could be helpful for interrupting Leishmania transmission" |
| Keywords: | "Animals Ecology Evolution, Molecular Female Genetic Variation Insect Vectors/genetics/parasitology/*physiology Leishmania infantum/genetics/pathogenicity Leishmaniasis, Visceral/*transmission Male Psychodidae/genetics/parasitology/*physiology Sex Attracta;" |
| Notes: | "MedlineMaingon, Rhayza D C Ward, Richard D Hamilton, James G C Bauzer, Luiz G S R Peixoto, Alexandre A eng Howard Hughes Medical Institute/ Research Support, Non-U.S. Gov't England 2007/11/21 Trends Parasitol. 2008 Jan; 24(1):12-7. doi: 10.1016/j.pt.2007.10.003. Epub 2007 Nov 26" |
