| Title: | "Introduction of methyl groups to acetate substituted chain of (Z)-5-decenyl acetate, a pheromone component of turnip moth,agrotis segetum: synthesis, single-sensillum recordings, and structure-activity relationships" |
| Author(s): | Jonsson S; Liljefors T; Hansson BS; |
| Address: | "Department of Organic Chemistry 3 Chemical Center, University of Lund, P.O. Box 124, S-221 00, Lund, Sweden" |
| ISSN/ISBN: | 0098-0331 (Print) 0098-0331 (Linking) |
| Abstract: | "Methyl-substituted analogs of (Z)-5-decenyl acetate, a pheromone component of the turnip moth,Agrotis segetum, have been synthesized and studied by electrophysiological single-sensillum recordings and molecular mechanics calculations [MM2(85)]. The analogs are monomethyl substituted in the 2, 3, 4, and 5 positions and geminally dimethyl substituted in the 2, 3, and 4 positions. The methyl groups have been employed as space probes to study the degree of steric complementarity between the acetate-substituted alkyl chain of the pheromone component and its receptor. The electrophysiological activities, interpreted in terms of a receptor interaction model, indicate significant steric repulsive interactions between the introduced methyl groups and the receptor. This implies a high degree of complementarity between the acetate-substituted alkyl chain of the natural pheromone component and its receptor" |
| Notes: | "PubMed-not-MEDLINEJonsson, S Liljefors, T Hansson, B S eng 1992/04/01 J Chem Ecol. 1992 Apr; 18(4):637-57. doi: 10.1007/BF00987825" |
