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J Cell Physiol

Title:		Electronic cigarette: A recent update of its toxic effects on humans
Author(s):		Huang SJ; Xu YM; Lau ATY;
Address:		"Laboratory of Cancer Biology and Epigenetics, Department of Cell Biology and Genetics, Shantou University Medical College, Shantou, Guangdong, People's Republic of China"
Journal Title:		J Cell Physiol
Year:		2018
Volume:		20180115
Issue:		6
Page Number:		4466 - 4478
DOI:		10.1002/jcp.26352
ISSN/ISBN:		1097-4652 (Electronic) 0021-9541 (Linking)
Abstract:		"Electronic cigarettes (e-cigarettes), battery-powered and liquid-vaporizing devices, were invented to replace the conventional cigarette (c-cigarette) smoking for the sake of reducing the adverse effects on multiple organ systems that c-cigarettes have induced. Although some of the identified harmful components in e-cigarettes were alleged to be measured in lower quantity than those in c-cigarettes, researchers unveiled that the toxic effects of e-cigarettes should not be understated. This review is sought for an attempt to throw light on several typical types of e-cigarette components (tobacco-specific nitrosamines, carbonyl compounds, and volatile organic compounds) by revealing their possible impacts on human bodies through different action mechanisms characterized by alteration of specific biomarkers on cellular and molecular levels. In addition, this review is intended to draw the limelight that like c-cigarettes, e-cigarettes could also be accompanied with toxic effects on whole human body, which are especially apparent on respiratory system. From head to foot, from physical aspect to chemical aspect, from genotype to phenotype, potential alterations will take place upon the intake of the liquid aerosol"
Keywords:		Aerosols Consumer Product Safety *Electronic Nicotine Delivery Systems Humans Inhalation Exposure/*adverse effects Nitrosamines/*adverse effects Risk Assessment Smoking Cessation/*methods Vaping/*adverse effects Volatile Organic Compounds/*adverse effects;
Notes:		"MedlineHuang, Shu-Jie Xu, Yan-Ming Lau, Andy T Y eng Research Support, Non-U.S. Gov't Review 2017/12/08 J Cell Physiol. 2018 Jun; 233(6):4466-4478. doi: 10.1002/jcp.26352. Epub 2018 Jan 15"