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Int J Occup Med Environ Health

Title:		Faster health deterioration among nail technicians occupationally exposed to low levels of volatile organic compounds
Author(s):		Gresner P; Swiercz R; Wasowicz W; Gromadzinska J;
Address:		"Nofer Institute of Occupational Medicine, Lodz, Poland (Department of Toxicology and Carcinogenesis). pgresner@imp.lodz.pl. Nofer Institute of Occupational Medicine, Lodz, Poland (Department of Toxicology and Carcinogenesis). radek@imp.lodz.pl. Nofer Institute of Occupational Medicine, Lodz, Poland (Department of Toxicology and Carcinogenesis). wojciech@imp.lodz.pl. Nofer Institute of Occupational Medicine, Lodz, Poland (Department of Toxicology and Carcinogenesis). jola@imp.lodz.pl"
Journal Title:		Int J Occup Med Environ Health
Year:		2017
Volume:		20161228
Issue:		3
Page Number:		469 - 483
DOI:		10.13075/ijomeh.1896.00854
ISSN/ISBN:		1896-494X (Electronic) 1232-1087 (Linking)
Abstract:		"OBJECTIVES: The study has aimed at investigating the subjective assessment of an individual's health status and comparing the prevalence of selected work-related symptoms among nail technicians occupationally exposed to volatile organic compounds (VOCs) to the one among control subjects. Associations between occupational exposure to VOCs and the incidence of adverse health effects were also analyzed. MATERIAL AND METHODS: The study involved 145 female nail technicians and 152 control subjects. Data on the prevalence of adverse health effects was collected using the researcher- made questionnaire and then analyzed by means of survival analysis methods. RESULTS: Only 22% of nail technicians as compared to 45% of control subjects described their current health status as 'excellent' or 'very good' (odds ratio (OR) = 0.4, 95% confidence interval (CI): 0.2-0.6, p < 0.00005). In general, 61% of nail technicians confirmed to have experienced any out of all symptoms considered in the study since the commencement of the job, which was significantly higher as compared to 17% of control subjects (adjusted OR = 2.8, 95% CI: 2.1-3.7, p < 0.0001). Estimated median length of the employment period free of investigated symptoms was significantly shorter among nail technicians as compared to controls (12 years vs. 33 years, p < 0.0001), consistent with almost 4-times increased hazard of the occurrence of such symptoms among the technicians (hazard ratio (HR) = 3.9, 95% CI: 2.7-5.7, p < 0.0001). Cox proportional hazard regression modeling revealed almost 5-times increased hazard of the occurrence of any symptoms among nail technicians exposed to higher levels of the mixture of VOCs as compared to those exposed to lower levels (HR = 4.9, 95% CI: 1-24.1, p = 0.05). CONCLUSIONS: All outcomes combined together indicate that nail technicians are subject to faster health deterioration, which may be assumed to be caused by occupational exposure to low levels of VOCs. Int J Occup Med Environ Health 2017;30(3):469-483"
Keywords:		"Adult Air Pollutants, Occupational/toxicity *Beauty Culture Female *Health Status Humans Middle Aged Occupational Exposure/*adverse effects/analysis Poland/epidemiology Surveys and Questionnaires Volatile Organic Compounds/*analysis/toxicity adverse healt;"
Notes:		"MedlineGresner, Peter Swiercz, Radoslaw Wasowicz, Wojciech Gromadzinska, Jolanta eng Poland 2017/05/10 Int J Occup Med Environ Health. 2017 May 8; 30(3):469-483. doi: 10.13075/ijomeh.1896.00854. Epub 2016 Dec 28"