| Title: | "Chemical Variation, Antimicrobial, Nitric Oxide Scavenging Activities and Tyrosinase Inhibition of Essential Oils and Solvent Extracts from Filipendula vulgaris Moench Growing in Turkey" |
| Author(s): | Fandakli S; Korkmaz B; Faiz O; Kilic G; Erik I; Terzioglu S; Yayli N; |
| Address: | "Department of Diet and Nutrition, Faculty of Health Sciences, Avrasya University, Trabzon, Turkey. Department of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University, Trabzon, Turkey. Department of Chemistry, Faculty of Arts and Sciences, Recep Tayyip Erdogan University, Rize, Turkey. Department of Forest Botany, Faculty of Forestry, Karadeniz Technical University, Trabzon, Turkey" |
| DOI: | 10.22037/ijpr.2021.114302.14786 |
| ISSN/ISBN: | 1735-0328 (Print) 1726-6890 (Electronic) 1726-6882 (Linking) |
| Abstract: | "Volatile organic compositions of the essential oils (EOs), solid-phase microextraction (SPME) and SPME of n-hexane extracts from the flower and stem-leaf of Filipendula vulgaris (F. vulgaris) were analyzed by GC-FID/MS. A total of 107 constituents were characterized, flower and stem-leaf parts of the plant were found to contain different volatile organic compounds. Tricosane (29.6%), n-nonanal (20.5%) were identified as the main components in the essential oil of the flower, while phytol (35.2%) was found to be a major constituent in the essential oil of stem-leaf. Benzaldehyde (56.0%) and n-nonanal (31.6%) were the major groups in the SPME of stem-leaf and flower, respectively. The volatiles for the SPME of n-hexane extracts of the flower and stem-leaf of F. vulgaris were predominated by aromatic compounds (75.0% and 78.5%) and ketones (18.1% and 10.1%), respectively. On the other hand, a total of terpene compounds was found at the most in the EO of the stem-leaf part of the plant (48.6%). In addition, antimicrobial, tyrosinase inhibition, and nitric oxide scavenging activities of the n-hexane (H), methanol (M), aqueous extracts (A) and EOs of F. vulgaris were investigated. EOs and methanol extracts of flower and stem-leaf had high antimicrobial activity against tested various microorganisms. However, n-hexane extracts of the flower and stem-leaf only displayed activity against Mycobacterium smegmatis. Methanol extracts of flower and stem-leaf possessed the best tyrosine inhibition and NO scavenging activity" |
| Keywords: | Filipendula vulgaris Gc-fid/ms Spme biological activity.essential oil; |
| Notes: | "PubMed-not-MEDLINEFandakli, Seda Korkmaz, Busra Faiz, Ozlem Kilic, Gozde Erik, Ishak Terzioglu, Salih Yayli, Nurettin eng Netherlands 2021/12/15 Iran J Pharm Res. 2021 Summer; 20(3):110-120. doi: 10.22037/ijpr.2021.114302.14786" |
