« Previous Abstract"Fresh, dried or smoked? Repellent properties of volatiles emitted from ethnomedicinal plant leaves against malaria and yellow fever vectors in Ethiopia"    Next AbstractIdentification of a polar region in transmembrane domain 6 that regulates the function of the G protein-coupled alpha-factor receptor »

Rapid Commun Mass Spectrom

Title:		Memory effects in combining isotope ratio monitoring with isotope dilution mass spectrometry
Author(s):		Dube G; Henrion A; Ohlendorf R;
Address:		"Physikalisch-Technische Bundesanstalt, Bundesallee 100, D-38116 Braunschweig, Germany"
Journal Title:		Rapid Commun Mass Spectrom
Year:		1999
Volume:		13
Issue:		12
Page Number:		1186 - 1188
DOI:		10.1002/(SICI)1097-0231(19990630)13:12<1186::AID-RCM635>3.0.CO;2-8
ISSN/ISBN:		1097-0231 (Electronic) 0951-4198 (Linking)
Abstract:		"Combining isotope ratio monitoring with isotope dilution techniques provides very accurate results in the quantitative analysis of volatile organic chemical compounds by gas chromatography/mass spectrometry (GC/MS). However, this method requires that spikes highly enriched in (13)C be used. This may lead to memory effects which will be investigated in more detail. They occur when the component of the mixture to be investigated exhibits an isotope ratio which is different from that of the component eluted earlier from the column during the chromatographic separation process. A residue of this component, which is shown in the gas chromatogram as tailing, falsifies the result of the isotope ratio measurement. This also leads to false amount-of-substance measurement results. Memory effects can be avoided by using spikes of low (13)C content, by adjusting the composition of the reference solution to that of the sample, or by ensuring effective sample preparation, thus separating disturbing mixture components prior to the measurement. Copyright 1999 John Wiley & Sons, Ltd"
Keywords:
Notes:		"PublisherDube, G Henrion, A Ohlendorf, R eng England 1999/07/17 Rapid Commun Mass Spectrom. 1999 Jun; 13(12):1186-1188. doi: 10.1002/(SICI)1097-0231(19990630)13:12<1186::AID-RCM635>3.0.CO; 2-8"