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Mutat Res

Title:		Mutagenic activity of non-volatile organic matter associated with suspended matter in urban air
Author(s):		de Wiest F; Rondia D; Gol-Winkler R; Gielen J;
Address:
Journal Title:		Mutat Res
Year:		1982
Volume:		104
Issue:		4-May
Page Number:		201 - 207
DOI:		10.1016/0165-7992(82)90145-2
ISSN/ISBN:		0027-5107 (Print) 0027-5107 (Linking)
Abstract:		"Extracts of atmospheric suspended matter showed a direct mutagenic effect in the Ames test. This effect was increased by metabolic activation. These extracts were separated into an aliphatic, an aromatic and a polar fraction. The aliphatic fraction had no effect, with or without activation; the aromatic fraction showed the greatest mutagenicity with and without activation; the polar fraction was also mutagenic, but its metabolic activation did not enhance the effect. The active compounds in this last fraction could be represented in a significant part by oxygenated derivatives of polycyclic aromatic hydrocarbons"
Keywords:		"Air/*analysis Animals Belgium Biotransformation Humans Microsomes, Liver/metabolism Mutagenicity Tests Mutagens/*isolation & purification *Mutation Rats Salmonella typhimurium/drug effects Urban Population;"
Notes:		"Medlinede Wiest, F Rondia, D Gol-Winkler, R Gielen, J eng Research Support, Non-U.S. Gov't Netherlands 1982/05/01 Mutat Res. 1982 May-Jun; 104(4-5):201-7. doi: 10.1016/0165-7992(82)90145-2"