| Title: | "Synthesis of some analogues of blattellastanoside A, the steroidal aggregation pheromone of the German cockroach" |
| Author(s): | Mori K; Nakayama T; Sakuma M; |
| Address: | "Department of Chemistry, Faculty of Science, Science University of Tokyo, Japan" |
| DOI: | 10.1016/0968-0896(96)00018-1 |
| ISSN/ISBN: | 0968-0896 (Print) 0968-0896 (Linking) |
| Abstract: | "Blattellastanoside A, the aggregation pheromone of the German cockroach, is a chlorinated steroid glucoside with the 5 beta-stigmastane skeleton. Its analogues were synthesized in order to clarify the structure-activity relationship. They are 1a with the 5 beta-cholestane skeleton, 1b with the 5 beta-androstane skeleton, 1c with a fluorine substituent instead of the chlorine and 1d with a beta-D-galactopyranose instead of the beta-D-glucopyranose of the original pheromone. Their bioassay shows that 1a and 1c are active, while 1b and 1d are totally devoid of pheromone activity. The aglycone of blattellastanosides A and B were active" |
| Keywords: | "Animals Behavior, Animal Biological Assay Cockroaches/*chemistry Magnetic Resonance Spectroscopy Saponins/*chemical synthesis Sex Attractants/*chemical synthesis Spectrophotometry, Infrared *Stigmasterol/*analogs & derivatives;" |
| Notes: | "MedlineMori, K Nakayama, T Sakuma, M eng Research Support, Non-U.S. Gov't England 1996/03/01 Bioorg Med Chem. 1996 Mar; 4(3):401-8. doi: 10.1016/0968-0896(96)00018-1" |
