| Title: | "Effects of the posterior hypophysis and ovary on pheromonal production in normal females and in the reproductive behavior of male rats treated with D,L-propranolol" |
| Author(s): | Zipper J; Bruzzone ME; Trujillo V; Balboa P; |
| Address: | "Department of Physiology, School of Medicine, University of Chile, Santiago" |
| ISSN/ISBN: | 0020-725X (Print) 0020-725X (Linking) |
| Abstract: | "Posterior hypophysis homogenates of female rats stimulated with epinephrine subcutaneously contain a pheromonal factor that increments significantly the incidence of fertile coitus after having been placed in the oronasal groove of rats in proestro (69.2% fertile coitus vs. 36.6% of control). These same homogenates obtained from spayed rats increment reproductive activity even more (80.0% fertile coitus). The homogenates do not act by an intraperitoneal route. Male rats under the effect of high doses of D,L-propranolol reduce reproductive activity (21.2% fertile coitus). This effect is counteracted by posterior hypophysis homogenates from female rats stimulated with epinephrine, placed in the oronasal groove (72.2% fertile coitus). The homogenates of anterior hypophysis do not increase the reproductive capacity of rats in proestro, and do not modify the propranolol effects in male rats" |
| Keywords: | "Animals Epinephrine/pharmacology Female Male Ovary/*drug effects/physiology Pheromones/*biosynthesis Pituitary Gland, Posterior/*drug effects/physiology Propranolol/*pharmacology Rats Rats, Inbred Strains Sex Attractants/*biosynthesis Sexual Behavior, Ani;" |
| Notes: | "MedlineZipper, J Bruzzone, M E Trujillo, V Balboa, P eng 1988/11/01 Int J Fertil. 1988 Nov-Dec; 33(6):426-31" |
