| Title: | Juvenile hormone and colony conditions differentially influence cytochrome P450 gene expression in the termite Reticulitermes flavipes |
| Author(s): | Zhou X; Song C; Grzymala TL; Oi FM; Scharf ME; |
| Address: | "Entomology and Nematology Department, University of Florida, Gainesville, FL 32611-0620, USA" |
| DOI: | 10.1111/j.1365-2583.2006.00675.x |
| ISSN/ISBN: | 0962-1075 (Print) 0962-1075 (Linking) |
| Abstract: | "In lower termites, the worker caste is a totipotent immature stage that is capable of differentiating into other adult caste phenotypes. We investigated the diversity of family 4 cytochrome P450 (CYP4) genes in Reticulitermes flavipes workers, with the specific goal of identifying P450s potentially involved in regulating caste differentiation. Seven novel CYP4 genes were identified. Quantitative real-time PCR revealed the tissue distribution of expression for the seven CYP4s, as well as temporal expression changes in workers in association with a release from colony influences and during juvenile hormone (JH)-induced soldier caste differentiation. Several fat-body-related CYP4 genes were differentially expressed after JH treatment. Still other genes changed expression in association with removal from colony influences, suggesting that primer pheromones and/or other colony influences impact their expression. These findings add to a growing database of candidate termite caste-regulatory genes, and provide explicit evidence that colony factors influence termite gene expression" |
| Keywords: | "Amino Acid Sequence Animals Base Sequence Cytochrome P-450 Enzyme System/*genetics DNA, Complementary/metabolism Gene Expression Regulation, Enzymologic/*drug effects Genes, Insect Insect Proteins/chemistry Introns/genetics Isoptera/*drug effects/*enzymol;" |
| Notes: | "MedlineZhou, X Song, C Grzymala, T L Oi, F M Scharf, M E eng Research Support, Non-U.S. Gov't England 2007/01/05 Insect Mol Biol. 2006 Dec; 15(6):749-61. doi: 10.1111/j.1365-2583.2006.00675.x" |
