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Wei Sheng Yan Jiu

Title:		[Effects of volatile organic compounds on brain amino acid neurotransmitter in mice]
Author(s):		Zhang H; Song W;
Address:		"School of Public Health, Fudan University, Shanghai 200032, China"
Journal Title:		Wei Sheng Yan Jiu
Year:		2007
Volume:		36
Issue:		3
Page Number:		269 - 272
DOI:
ISSN/ISBN:		1000-8020 (Print) 1000-8020 (Linking)
Abstract:		"OBJECTIVE: Study adverse effects of volatile organic compounds volatile organic compounds (VOCs) on brain amino acid neurotransmitter in mice. METHODS: Four groups of mouse were respectively exposed to 0, low, middle and high concentration of VOCs for two hours every day for 30 days. The content of brain amino acid neurotransmitter was determined. RESULTS: The result showed that the content of Glu and ASP in brain of VOCs -exposed mouse decreased and GABA and Gly increased compared with that of control. CONCLUSION: The memory impair in mice induced by exposing VOCs may relate to the chang of content of amino acid neurotransmitter"
Keywords:		Amino Acids/*metabolism Animals Aspartic Acid/metabolism Brain/*metabolism Brain Chemistry Female Glutamic Acid/metabolism Male Mice Neurotransmitter Agents/*metabolism Random Allocation Volatile Organic Compounds/*toxicity gamma-Aminobutyric Acid/metabol;
Notes:		"MedlineZhang, Huanzhu Song, Weimin chi English Abstract China 2007/08/24 Wei Sheng Yan Jiu. 2007 May; 36(3):269-72"