| Title: | Characteristic Volatile Composition of Seven Seaweeds from the Yellow Sea of China |
| Author(s): | Wang P; Chen J; Chen L; Shi L; Liu H; |
| Address: | "Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China. Laboratory for Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), Qingdao 266237, China" |
| ISSN/ISBN: | 1660-3397 (Electronic) 1660-3397 (Linking) |
| Abstract: | "Plant volatile organic compounds (VOCs) represent a relatively wide class of secondary metabolites. The VOC profiles of seven seaweeds (Grateloupia filicina, Polysiphonia senticulosa, Callithamnion corymbosum, Sargassum thunbergii, Dictyota dichotoma, Enteromorpha prolifera and Ulva lactuca) from the Yellow Sea of China were investigated using multifiber headspace solid phase microextraction coupled with gas chromatography-mass spectrometry (HS-SPME/GC-MS), among them, the VOCs of three red algae Grateloupia filicina, Polysiphonia senticulosa, and Callithamnion corymbosum were first reported. Principal component analysis (PCA) was used to disclose characteristic categories and molecules of VOCs and network pharmacology was performed to predict potential biomedical utilization of candidate seaweeds. Aldehyde was found to be the most abundant VOC category in the present study and (E)-beta-ionone was the only compound found to exist in all seven seaweeds. The chemical diversity of aldehydes in E. prolifera suggest its potential application in chemotaxonomy and hinted that divinylbenzene/carboxen/polydimethylsiloxane (DVB/CAR/PDMS) fiber is more suitable for aldehyde extraction. VOCs in D. dichotoma were characterized as sesquiterpenes and diterpenes and the most relevant pharmacological pathway was the neuroactive ligand-receptor interaction pathway, which suggests that D. dichotoma may have certain preventive and therapeutic values in cancer, especially in lung cancer, in addition to neuropsychiatric diseases" |
| Keywords: | Aldehydes/*isolation & purification/pharmacology Animals Antineoplastic Agents/isolation & purification/pharmacology Central Nervous System Agents/isolation & purification/pharmacology Diterpenes/isolation & purification/*pharmacology Gas Chromatography-M; |
| Notes: | "MedlineWang, Pengrui Chen, Jiapeng Chen, Lujing Shi, Li Liu, Hongbing eng 81973433/National Natural Science Foundation of China/ Switzerland 2021/04/04 Mar Drugs. 2021 Mar 29; 19(4):192. doi: 10.3390/md19040192" |
